U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Srek1ip1 SREK1-interacting protein 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361888, updated on 9-Dec-2024

    Summary

    Official Symbol
    Srek1ip1provided by RGD
    Official Full Name
    SREK1-interacting protein 1provided by RGD
    Primary source
    RGD:1305356
    See related
    EnsemblRapid:ENSRNOG00000047506 AllianceGenome:RGD:1305356
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    P18srp; Sfrs12ip1; RGD1305356
    Summary
    Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be involved in RNA splicing and mRNA processing. Orthologous to human SREK1IP1 (SREK1 interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 135.9), Spleen (RPKM 134.1) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Srek1ip1 in Genome Data Viewer
    Location:
    2q13
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (37709712..37733391)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (35975978..35999636)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (34923187..34940410)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S29, pseudogene 14 Neighboring gene CWC27 spliceosome associated cyclophilin Neighboring gene shisa like 2B Neighboring gene regulator of G-protein signaling 7 binding protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC105985

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein SREK1IP1
    Names
    SFRS12-interacting protein 1
    protein SFRS12IP1
    splicing regulatory glutamine/lysine-rich protein 1 interacting protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008373.2NP_001008374.1  protein SREK1IP1

      See identical proteins and their annotated locations for NP_001008374.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/Swiss-Prot
      Q5RJP9
      UniProtKB/TrEMBL
      A0A8I6AEB3, A6I5G3
      Related
      ENSRNOP00000064069.3, ENSRNOT00000074499.4
      Conserved Domains (1) summary
      pfam13917
      Location:930
      zf-CCHC_3; Zinc knuckle

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      37709712..37733391
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063282031.1XP_063138101.1  protein SREK1IP1 isoform X1