Jakmip2 janus kinase and microtubule interacting protein 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Jakmip2provided by RGD
Official Full Name: janus kinase and microtubule interacting protein 2provided by RGD
Primary source: RGD:1559742
See related: EnsemblRapid:ENSRNOG00000019159 AllianceGenome:RGD:1559742
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1559742
Summary: Predicted to enable kinase binding activity and microtubule binding activity. Predicted to be located in Golgi apparatus. Orthologous to human JAKMIP2 (janus kinase and microtubule interacting protein 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 97.2) See more
Orthologs: human mouse all
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Genomic context

Location:: 18q11

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	18	NC_086036.1 (35783472..35998849, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	18	NC_051353.1 (35532552..35747938, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	18	NC_005117.4 (37868645..38088530, complement)

Chromosome 18 - NC_086036.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

NECC 1 & 2 proteins primarily expressed in (neuro)endocrine tissues in vertebrates thus supporting a role for these proteins in the regulated secretory pathway.
Title: Identification and characterization of two novel (neuro)endocrine long coiled-coil proteins.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables kinase binding	IEA Inferred from Electronic Annotation more info
enables microtubule binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: janus kinase and microtubule-interacting protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001107391.1 → NP_001100861.1 janus kinase and microtubule-interacting protein 2

See identical proteins and their annotated locations for NP_001100861.1

Status: PROVISIONAL

Source sequence(s)

CH473974

UniProtKB/TrEMBL

A0A0G2JT21, A6J3M0, A6J3M1

Related

ENSRNOP00000068539.2, ENSRNOT00000077814.3

Conserved Domains (2) summary

COG1196
Location:24 → 804

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

pfam16034
Location:410 → 602

JAKMIP_CC3; JAKMIP CC3 domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086036.1 Reference GRCr8

Range

35783472..35998849 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063277367.1 → XP_063133437.1 janus kinase and microtubule-interacting protein 2 isoform X6

UniProtKB/TrEMBL

A6J3M0
XM_039096861.2 → XP_038952789.1 janus kinase and microtubule-interacting protein 2 isoform X5

UniProtKB/TrEMBL

A6J3M0

Conserved Domains (2) summary

COG1196
Location:4 → 774

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

pfam16034
Location:368 → 560

JAKMIP_CC3; JAKMIP CC3 domain
XM_039096857.2 → XP_038952785.1 janus kinase and microtubule-interacting protein 2 isoform X1

UniProtKB/TrEMBL

A6J3M0

Related

ENSRNOP00000104777.1, ENSRNOT00000142197.1

Conserved Domains (2) summary

COG1196
Location:24 → 816

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

pfam16034
Location:410 → 602

JAKMIP_CC3; JAKMIP CC3 domain
XM_063277365.1 → XP_063133435.1 janus kinase and microtubule-interacting protein 2 isoform X3

UniProtKB/TrEMBL

A6J3M0
XM_063277366.1 → XP_063133436.1 janus kinase and microtubule-interacting protein 2 isoform X4

UniProtKB/TrEMBL

A6J3M0, D3ZQE7

Related

ENSRNOP00000025926.8, ENSRNOT00000025927.9
XM_063277364.1 → XP_063133434.1 janus kinase and microtubule-interacting protein 2 isoform X2

UniProtKB/TrEMBL

A0A8I6A3T9, A6J3M0, A6J3M2

Related

ENSRNOP00000087222.1, ENSRNOT00000100829.2