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    Adgrg5 adhesion G protein-coupled receptor G5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307645, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Adgrg5provided by RGD
    Official Full Name
    adhesion G protein-coupled receptor G5provided by RGD
    Primary source
    RGD:1305559
    See related
    EnsemblRapid:ENSRNOG00000039891 AllianceGenome:RGD:1305559
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Gpr114
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human ADGRG5 (adhesion G protein-coupled receptor G5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 32.4), Thymus (RPKM 16.7) and 7 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Adgrg5 in Genome Data Viewer
    Location:
    19p13
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (10080800..10104659, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (10074787..10098640, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (10495517..10514701, complement)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene adhesion G protein-coupled receptor G3 Neighboring gene adhesion G protein-coupled receptor G1 Neighboring gene coiled-coil domain containing 102A Neighboring gene docking protein 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    adhesion G-protein coupled receptor G5
    Names
    G protein-coupled receptor 114
    G protein-coupled receptor 114-like
    probable G-protein coupled receptor 114

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107410.1 → NP_001100880.1  adhesion G-protein coupled receptor G5 precursor

      See identical proteins and their annotated locations for NP_001100880.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474006
      UniProtKB/TrEMBL
      A6JY35
      Conserved Domains (3) summary
      pfam01825
      Location:184 → 228
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:242 → 267
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:242 → 513
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      10080800..10104659 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039097707.2 → XP_038953635.1  adhesion G-protein coupled receptor G5 isoform X10

      Conserved Domains (3) summary
      pfam01825
      Location:184 → 228
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:243 → 268
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:243 → 349
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    2. XM_039097706.2 → XP_038953634.1  adhesion G-protein coupled receptor G5 isoform X10

      Conserved Domains (3) summary
      pfam01825
      Location:184 → 228
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:243 → 268
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:243 → 349
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    3. XM_063277985.1 → XP_063134055.1  adhesion G-protein coupled receptor G5 isoform X3

    4. XM_008772297.2 → XP_008770519.2  adhesion G-protein coupled receptor G5 isoform X1

      Conserved Domains (3) summary
      pfam01825
      Location:184 → 228
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:242 → 267
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:242 → 348
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    5. XM_063277986.1 → XP_063134056.1  adhesion G-protein coupled receptor G5 isoform X8

    6. XM_008772299.3 → XP_008770521.2  adhesion G-protein coupled receptor G5 isoform X4

      Conserved Domains (3) summary
      pfam01825
      Location:184 → 228
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:243 → 268
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:243 → 322
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    7. XM_008772307.4 → XP_008770529.2  adhesion G-protein coupled receptor G5 isoform X6

      UniProtKB/TrEMBL
      A6JY35
      Conserved Domains (3) summary
      pfam01825
      Location:184 → 228
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:242 → 267
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:242 → 513
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    8. XM_008772298.3 → XP_008770520.2  adhesion G-protein coupled receptor G5 isoform X2

      Conserved Domains (3) summary
      pfam01825
      Location:184 → 228
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:243 → 268
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:243 → 272
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    9. XM_017601274.3 → XP_017456763.2  adhesion G-protein coupled receptor G5 isoform X7

      Conserved Domains (3) summary
      pfam01825
      Location:184 → 228
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:243 → 268
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:243 → 315
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    10. XM_008772306.4 → XP_008770528.2  adhesion G-protein coupled receptor G5 isoform X5

      UniProtKB/TrEMBL
      F1M644
      Related
      ENSRNOP00000057982.4, ENSRNOT00000061270.6
      Conserved Domains (3) summary
      pfam01825
      Location:184 → 228
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:243 → 268
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:243 → 514
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    11. XM_063277987.1 → XP_063134057.1  adhesion G-protein coupled receptor G5 isoform X9

    12. XM_008772301.4 → XP_008770523.1  adhesion G-protein coupled receptor G5 isoform X10

      See identical proteins and their annotated locations for XP_008770523.1

      Conserved Domains (3) summary
      pfam01825
      Location:184 → 228
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:243 → 268
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:243 → 349
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    13. XM_063277989.1 → XP_063134059.1  adhesion G-protein coupled receptor G5 isoform X13

    14. XM_063277988.1 → XP_063134058.1  adhesion G-protein coupled receptor G5 isoform X12

    15. XM_039097708.2 → XP_038953636.1  adhesion G-protein coupled receptor G5 isoform X11

      Conserved Domains (3) summary
      pfam01825
      Location:184 → 228
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:243 → 268
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:243 → 269
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RNA

    1. XR_005496649.2 RNA Sequence

    2. XR_005496648.2 RNA Sequence

    3. XR_005496650.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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