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    YBP2 Ybp2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852820, updated on 9-Dec-2024

    Summary

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    Official Symbol
    YBP2
    Official Full Name
    Ybp2p
    Primary source
    SGD:S000003028
    Locus tag
    YGL060W
    See related
    AllianceGenome:SGD:S000003028; FungiDB:YGL060W; VEuPathDB:YGL060W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    YBH1
    Summary
    Involved in mitotic spindle organization. Located in kinetochore. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See YBP2 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (390065..391990)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene pyruvate carboxylase 1 Neighboring gene Duo1p Neighboring gene protein kinase PKP2 Neighboring gene E2 ubiquitin-conjugating protein RAD6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. YBP1 and its homologue YBP2/YBH1 influence oxidative-stress tolerance by nonidentical mechanisms in Saccharomyces cerevisiae. Gulshan K, et al. Eukaryot Cell, 2004 Apr. PMID 15075262, Free PMC Article
    2. Suppressors of ipl1-2 in components of a Glc7 phosphatase complex, Cdc48 AAA ATPase, TORC1, and the kinetochore. Robinson LC, et al. G3 (Bethesda), 2012 Dec. PMID 23275890, Free PMC Article
    3. Ybp2 associates with the central kinetochore of Saccharomyces cerevisiae and mediates proper mitotic progression. Ohkuni K, et al. PLoS One, 2008 Feb 20. PMID 18286174, Free PMC Article
    4. A network of proteins around Rvs167p and Rvs161p, two proteins related to the yeast actin cytoskeleton. Bon E, et al. Yeast, 2000 Sep 30. PMID 10992286
    5. Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction. Bennett CB, et al. PLoS One, 2008 Jan 16. PMID 18197258, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to oxidative stress IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cellular response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitotic spindle organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Ybp2p
    NP_011455.1
    • Central kinetochore associated protein; mediates mitotic progression; interacts with several central kinetochore proteins and centromeric histone Cse4p; role in resistance to oxidative stress; similar to Slk19p; YBP2 has a paralog, YBP1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      390065..391990
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180925.1 → NP_011455.1  TPA: Ybp2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011455.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VU81, P53169
      UniProtKB/TrEMBL
      B3LHC9, C7GRJ6
      Conserved Domains (1) summary
      pfam08568
      Location:1 → 633
      Kinetochor_Ybp2; Uncharacterized protein family, YAP/Alf4/glomulin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53169.1

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