U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    RPS21A ribosomal 40S subunit protein S21A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853931, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    RPS21A
    Official Full Name
    ribosomal 40S subunit protein S21A
    Primary source
    SGD:S000001765
    Locus tag
    YKR057W
    See related
    AllianceGenome:SGD:S000001765; FungiDB:YKR057W; VEuPathDB:YKR057W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RPS25
    Summary
    A structural constituent of ribosome. Involved in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Part of cytosolic small ribosomal subunit. Orthologous to human RPS21 (ribosomal protein S21). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See RPS21A in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    2
    Sequence:
    Chromosome: XI; NC_001143.9 (551657..552242)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene Rho family GTPase RHO4 Neighboring gene tRNA (uracil(54)-C(5))-methyltransferase Neighboring gene glycogenin glucosyltransferase GLG1 Neighboring gene translation initiation factor eIF4A

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Examination of protein sequence homologies: III. Ribosomal protein YS25 from Saccharomyces cerevisiae and its counterparts from Schizosaccharomyces pombe, rat liver, and Escherichia coli. Otaka E, et al. J Mol Evol, 1986. PMID 3104606
    2. Primary structures of ribosomal protein YS25 from Saccharomyces cerevisiae and its counterparts from Schizosaccharomyces pombe and rat liver. Itoh T, et al. Biochemistry, 1985 Dec 3. PMID 3910104
    3. RPS25 is essential for translation initiation by the Dicistroviridae and hepatitis C viral IRESs. Landry DM, et al. Genes Dev, 2009 Dec 1. PMID 19952110, Free PMC Article
    4. Ribosomal proteins Rps0 and Rps21 of Saccharomyces cerevisiae have overlapping functions in the maturation of the 3' end of 18S rRNA. Tabb-Massey A, et al. Nucleic Acids Res, 2003 Dec 1. PMID 14627813, Free PMC Article
    5. Protein topography of the 40 S ribosomal subunit from Saccharomyces cerevisiae as shown by chemical cross-linking. Yeh YC, et al. J Biol Chem, 1986 Oct 25. PMID 3533916

    See all (72) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. function of Rps25 is conserved across internal ribosome entry site types
      Title: RPS25 is essential for translation initiation by the Dicistroviridae and hepatitis C viral IRESs.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    ribosomal 40S subunit protein S21A
    NP_012983.3
    • Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S21, no bacterial homolog; RPS21A has a paralog, RPS21B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      551657..552242
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179847.3 → NP_012983.3  TPA: ribosomal 40S subunit protein S21A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012983.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VXB8, P0C0V8
      UniProtKB/TrEMBL
      A7A017, B3LRD2, C7GPZ3, C8ZCM0, G2WI85, N1P0Y2
      Conserved Domains (1) summary
      pfam01249
      Location:1 → 80
      Ribosomal_S21e; Ribosomal protein S21e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0C0V8.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools