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    ARA2 D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA2 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855057, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ARA2
    Official Full Name
    D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA2
    Primary source
    SGD:S000004644
    Locus tag
    YMR041C
    See related
    AllianceGenome:SGD:S000004644; FungiDB:YMR041C; VEuPathDB:YMR041C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables D-arabinose 1-dehydrogenase [NAD(P)+] activity. Involved in dehydro-D-arabinono-1,4-lactone biosynthetic process. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ARA2 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (350966..351973, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene chromatin-binding transcription coactivator SUB1 Neighboring gene Yet2p Neighboring gene tRNA-Phe Neighboring gene Arg80p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. NAD+-specific D-arabinose dehydrogenase and its contribution to erythroascorbic acid production in Saccharomyces cerevisiae. Amako K, et al. FEBS Lett, 2006 Nov 27. PMID 17097644
    2. Btn3 regulates the endosomal sorting function of the yeast Ent3 epsin, an adaptor for SNARE proteins. Morvan J, et al. J Cell Sci, 2015 Feb 15. PMID 25512335
    3. Comparative analysis of Saccharomyces cerevisiae WW domains and their interacting proteins. Hesselberth JR, et al. Genome Biol, 2006. PMID 16606443, Free PMC Article
    4. Functional profiling of the Saccharomyces cerevisiae genome. Giaever G, et al. Nature, 2002 Jul 25. PMID 12140549
    5. Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae. Kyriakou D, et al. BMC Biol, 2016 Dec 7. PMID 27927215, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. It demonstrates that Ara2p, not Ara1p, mainly contributes to the production of Erythroascorbic acid from d-arabinose in S. cerevisiae.
      Title: NAD+-specific D-arabinose dehydrogenase and its contribution to erythroascorbic acid production in Saccharomyces cerevisiae.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables D-arabinose 1-dehydrogenase (NAD+) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables D-arabinose 1-dehydrogenase [NAD(P)+] activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables D-arabinose 1-dehydrogenase [NAD(P)+] activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables D-arabinose 1-dehydrogenase [NAD(P)+] activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables D-arabinose 1-dehydrogenase [NAD(P)+] activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in dehydro-D-arabinono-1,4-lactone biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in dehydro-D-arabinono-1,4-lactone biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA2
    NP_013755.1
    • NAD-dependent arabinose dehydrogenase; involved in biosynthesis of dehydro-D-arabinono-1,4-lactone; similar to plant L-galactose dehydrogenase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      350966..351973 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182538.1 → NP_013755.1  TPA: D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA2 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013755.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZL6, Q04212, Q1XGQ6
      UniProtKB/TrEMBL
      A6ZMA3, B3LLU0, B5VPH1, C7GL78, C8ZEP8, G2WK94, N1NY81
      Conserved Domains (1) summary
      cd19164
      Location:2 → 301
      AKR_ARA2; D-arabinose 1-dehydrogenase (ARA2) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04212.1

    Gene LinkOut

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