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    DIT1 Dit1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852012, updated on 9-Dec-2024

    Summary

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    Official Symbol
    DIT1
    Official Full Name
    Dit1p
    Primary source
    SGD:S000002811
    Locus tag
    YDR403W
    See related
    AllianceGenome:SGD:S000002811; FungiDB:YDR403W; VEuPathDB:YDR403W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables catalytic activity. Involved in ascospore wall assembly. Located in ascospore-type prospore and cytosol. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See DIT1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1274602..1276212)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene trifunctional uridine nucleosidase/nicotinamide riboside hydrolase/nicotinic acid riboside hydrolase Neighboring gene putative cytochrome P450 Neighboring gene DNA-directed RNA polymerase II subunit RPB7 Neighboring gene mitochondrial 54S ribosomal protein YmL41

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation of two developmentally regulated genes involved in spore wall maturation in Saccharomyces cerevisiae. Briza P, et al. Genes Dev, 1990 Oct. PMID 2249774
    2. Studies on the Properties of the Sporulation Specific Protein Dit1 and its Product Formyl Tyrosine. Basiony M, et al. J Fungi (Basel), 2020 Jun 3. PMID 32503197, Free PMC Article
    3. An Ssn6-Tup1-dependent negative regulatory element controls sporulation-specific expression of DIT1 and DIT2 in Saccharomyces cerevisiae. Friesen H, et al. Mol Cell Biol, 1997 Jan. PMID 8972192, Free PMC Article
    4. Characterization of a yeast sporulation-specific P450 family protein, Dit2, using an in vitro assay to crosslink formyl tyrosine. Bemena LD, et al. J Biochem, 2018 Feb 1. PMID 29365103
    5. Gene expression from random libraries of yeast promoters. Ligr M, et al. Genetics, 2006 Apr. PMID 16415362, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Rpd3-Complex Regulates Expression of Multiple Cell Surface Recycling Factors in Yeast.
      Title: The Rpd3-Complex Regulates Expression of Multiple Cell Surface Recycling Factors in Yeast.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables catalytic activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ascospore wall assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in ascospore wall assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in ascospore-type prospore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Dit1p
    NP_010691.1
    • Sporulation-specific enzyme required for spore wall maturation; involved in the production of a soluble LL-dityrosine-containing precursor of the spore wall; transcripts accumulate at the time of prospore enclosure

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1274602..1276212
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180711.1 → NP_010691.1  TPA: Dit1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010691.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VT35, P21623
      UniProtKB/TrEMBL
      G2WBE1, N1P757
      Conserved Domains (1) summary
      COG3207
      Location:156 → 525
      Dit1; Pyoverdine/dityrosine biosynthesis protein Dit1 [Secondary metabolites biosynthesis, transport and catabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P21623.2

    Gene LinkOut

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