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    MSC3 Msc3p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850916, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MSC3
    Official Full Name
    Msc3p
    Primary source
    SGD:S000004209
    Locus tag
    YLR219W
    See related
    AllianceGenome:SGD:S000004209; FungiDB:YLR219W; VEuPathDB:YLR219W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in reciprocal meiotic recombination. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MSC3 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (574151..576337)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase CPR6 Neighboring gene Coa4p Neighboring gene Ccc1p Neighboring gene Rsa3p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Seg1 controls eisosome assembly and shape. Moreira KE, et al. J Cell Biol, 2012 Aug 6. PMID 22869600, Free PMC Article
    2. Genetic control of recombination partner preference in yeast meiosis. Isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination. Thompson DA, et al. Genetics, 1999 Oct. PMID 10511544, Free PMC Article
    3. A role for eisosomes in maintenance of plasma membrane phosphoinositide levels. Fröhlich F, et al. Mol Biol Cell, 2014 Sep 15. PMID 25057013, Free PMC Article
    4. Nicotinamide induces Fob1-dependent plasmid integration into chromosome XII in Saccharomyces cerevisiae. Tripathi K, et al. FEMS Yeast Res, 2012 Dec. PMID 22909099
    5. Unifying fluorescence microscopy and mass spectrometry for studying protein complexes in cells. Deng C, et al. Mol Cell Proteomics, 2009 Jun. PMID 19269952, Free PMC Article

    See all (47) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA recombination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in reciprocal meiotic recombination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Msc3p
    NP_013320.1
    • hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; msc3 mutants are defective in directing meiotic recombination events to homologous chromatids; potential Cdc28p substrate; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      574151..576337
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182106.1 → NP_013320.1  TPA: Msc3p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013320.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VYL9, Q05812, Q7LIF4
      UniProtKB/TrEMBL
      C7GIU7, C8ZDI3, N1P1C8
      Conserved Domains (2) summary
      PHA03255
      Location:573 → 718
      PHA03255; BDLF3; Provisional
      cl27202
      Location:207 → 384
      Mpp10; Mpp10 protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q05812.1

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