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    CG4611 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38601, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4611provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035591
    Locus tag
    Dmel_CG4611
    See related
    AllianceGenome:FB:FBgn0035591
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4611
    Summary
    Predicted to enable tRNA binding activity. Predicted to be involved in tRNA 3'-end processing. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix. Orthologous to human PTCD1 (pentatricopeptide repeat domain 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4611 in Genome Data Viewer
    Location:
    64C7-64C7; 3-13 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (5136376..5138679)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (5129476..5131779)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Yod1 deubiquitinase Neighboring gene antisense RNA:CR45160 Neighboring gene uncharacterized protein Neighboring gene Threonyl-carbamoyl synthesis 5 Neighboring gene Charged multivesicular body protein 2b Neighboring gene Dehydrogenase/reductase 4 Neighboring gene long non-coding RNA:CR45985 Neighboring gene Gdap1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The PPR domain of mitochondrial RNA polymerase is an exoribonuclease required for mtDNA replication in Drosophila melanogaster. Liu Y, et al. Nat Cell Biol, 2022 May. PMID 35449456
    2. Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila. Vesala L, et al. BMC Biol, 2024 Mar 13. PMID 38475850, Free PMC Article
    3. Identification of novel genes associated with longevity in Drosophila melanogaster - a computational approach. Hall BS, et al. Aging (Albany NY), 2019 Dec 3. PMID 31794428, Free PMC Article
    4. Identification of genes that promote or inhibit olfactory memory formation in Drosophila. Walkinshaw E, et al. Genetics, 2015 Apr. PMID 25644700, Free PMC Article
    5. Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Çiçek IÖ, et al. Genetics, 2016 Mar. PMID 26801178, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables tRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in tRNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tRNA 3'-end processing ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4611-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      5136376..5138679
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139692.3 → NP_647949.1  uncharacterized protein Dmel_CG4611 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647949.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VRJ7
      Related
      FBpp0076868
      Conserved Domains (4) summary
      sd00004
      Location:186 → 213
      PPR; PPR repeat [structural motif]
      pfam01535
      Location:185 → 215
      PPR; PPR repeat
      pfam12854
      Location:252 → 284
      PPR_1; PPR repeat
      pfam13041
      Location:256 → 304
      PPR_2; PPR repeat family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VRJ7 Q9VRJ7

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