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    CG6770 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34621, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6770provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032400
    Locus tag
    Dmel_CG6770
    See related
    AllianceGenome:FB:FBgn0032400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO02059370.25; CT21019; Dmel\CG6770; p8
    Summary
    Predicted to be involved in negative regulation of cell cycle; negative regulation of cell population proliferation; and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including NUPR1 (nuclear protein 1, transcriptional regulator). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6770 in Genome Data Viewer
    Location:
    33B11-33B11; 2-45 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (12045343..12046118, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (12045343..12046118, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR46070 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44589 Neighboring gene Promyelocytic leukemia zinc finger

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Drosophila FoxA ortholog Fork head regulates growth and gene expression downstream of Target of rapamycin. Bülow MH, et al. PLoS One, 2010 Dec 31. PMID 21217822, Free PMC Article
    2. The Amino Acid Transporter JhI-21 Coevolves with Glutamate Receptors, Impacts NMJ Physiology, and Influences Locomotor Activity in Drosophila Larvae. Ziegler AB, et al. Sci Rep, 2016 Jan 25. PMID 26805723, Free PMC Article
    3. Dietary Adaptation of Microbiota in Drosophila Requires NF-κB-Dependent Control of the Translational Regulator 4E-BP. Vandehoef C, et al. Cell Rep, 2020 Jun 9. PMID 32521261, Free PMC Article
    4. Forkhead, a new cross regulator of metabolism and innate immunity downstream of TOR in Drosophila. Varma D, et al. J Insect Physiol, 2014 Oct. PMID 24842780
    5. Differences in Postmating Transcriptional Responses between Conspecific and Heterospecific Matings in Drosophila. Ahmed-Braimah YH, et al. Mol Biol Evol, 2021 Mar 9. PMID 33035303, Free PMC Article

    See all (55) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in negative regulation of cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of cell population proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6770-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      12045343..12046118 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135695.2 → NP_609539.1  uncharacterized protein Dmel_CG6770 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609539.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VKC5
      Related
      FBpp0079890
      Conserved Domains (1) summary
      pfam10195
      Location:3 → 55
      Phospho_p8; DNA-binding nuclear phosphoprotein p8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VKC5 Q9VKC5

    Gene LinkOut

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