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    nht no hitter [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34902, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nhtprovided by FlyBase
    Official Full Name
    no hitterprovided by FlyBase
    Primary source
    FLYBASE:FBgn0041103
    Locus tag
    Dmel_CG15259
    See related
    AllianceGenome:FB:FBgn0041103
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BG:DS07851.6; CG15259; Dmel\CG15259; dmTAF4b; DS07851.6; dTAF4L; dTAF[[II]]110; Nht; TAF4; Taf4L; TFIID
    Summary
    Enables protein heterodimerization activity. Involved in regulation of gene expression and spermatogenesis. Located in male germ cell nucleus and nucleolus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See nht in Genome Data Viewer
    Location:
    35D1-35D1; 2-51 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (15317954..15318901, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (15317954..15318901, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43764 Neighboring gene uncharacterized protein Neighboring gene escargot Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. To be or not be (in the LAD): emerging roles of lamin proteins in transcriptional regulation. Nazer E. Biochem Soc Trans, 2022 Apr 29. PMID 35437578, Free PMC Article
    2. Combinatorial control of temporal gene expression in the Drosophila wing by enhancers and core promoters. O'Keefe DD, et al. BMC Genomics, 2012 Sep 20. PMID 22992320, Free PMC Article
    3. mgm 1, the earliest sex-specific germline marker in Drosophila, reflects expression of the gene esg in male stem cells. Streit A, et al. Int J Dev Biol, 2002 Jan. PMID 11902678
    4. The DrosDel deletion collection: a Drosophila genomewide chromosomal deficiency resource. Ryder E, et al. Genetics, 2007 Sep. PMID 17720900, Free PMC Article
    5. Approaches to defining the ancestral eukaryotic protein complexome. Ceulemans H, et al. Bioessays, 2006 Mar. PMID 16479579

    See all (53) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    contributes_to RNA polymerase II general transcription initiation factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein heterodimerization activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription initiation at RNA polymerase II promoter ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in male germ cell nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of transcription factor TFIID complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIID complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    no hitter
    Names
    CG15259-PB
    nht-PB
    nohitter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      15317954..15318901 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078850.4 → NP_523574.4  no hitter [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523574.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V6W2, Q5UEC5, Q9NK90, Q9VJP5
      Conserved Domains (1) summary
      cd08045
      Location:10 → 238
      TAF4; TATA Binding Protein (TBP) Associated Factor 4 (TAF4) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5UEC5 Q5UEC5
    Q9VJP5 Q9VJP5

    Gene LinkOut

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