U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG3309 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31450, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG3309provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029756
    Locus tag
    Dmel_CG3309
    See related
    AllianceGenome:FB:FBgn0029756
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BEST:LD39762; Dmel\CG3309
    Summary
    Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be active in recycling endosome. Orthologous to human DENND6A (DENN domain containing 6A) and DENND6B (DENN domain containing 6B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG3309 in Genome Data Viewer
    Location:
    4F5-4F5; 1-11 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5326675..5329347, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (5220708..5223380, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Something about silencing 10 Neighboring gene RNA-binding protein 4F Neighboring gene Minichromosome maintenance 3 Neighboring gene XRCC1 Neighboring gene Calcineurin B

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Mcm3 replicative helicase mutation impairs neuroblast proliferation and memory in Drosophila. Blumröder R, et al. Genes Brain Behav, 2016 Sep. PMID 27283469, Free PMC Article
    2. Genome-wide study of aging and oxidative stress response in Drosophila melanogaster. Zou S, et al. Proc Natl Acad Sci U S A, 2000 Dec 5. PMID 11095759, Free PMC Article
    3. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    4. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
    5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in recycling endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG3309-PA
    CG3309-PB

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      5326675..5329347 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001297956.1 → NP_001284885.1  uncharacterized protein Dmel_CG3309, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284885.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2JCL3
      Conserved Domains (1) summary
      pfam08616
      Location:270 → 363
      SPA; Stabilization of polarity axis

    2. NM_131988.3 → NP_572216.1  uncharacterized protein Dmel_CG3309, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572216.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W4D1
      Related
      FBpp0070764
      Conserved Domains (1) summary
      pfam08616
      Location:270 → 368
      SPA; Stabilization of polarity axis
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W4D1 Q9W4D1
    X2JCL3 X2JCL3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous