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    Acbp5 Acyl-CoA binding protein 5 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39005, updated on 17-Dec-2024

    Summary

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    Official Symbol
    Acbp5provided by FlyBase
    Official Full Name
    Acyl-CoA binding protein 5provided by FlyBase
    Primary source
    FLYBASE:FBgn0035926
    Locus tag
    Dmel_CG5804
    See related
    AllianceGenome:FB:FBgn0035926
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    ACBP; BcDNA:RE05521; CG5804; DmCG5804; Dmel\CG5804
    Summary
    Predicted to enable long-chain fatty acyl-CoA binding activity. Predicted to be involved in fatty acid metabolic process. Is expressed in embryonic/larval midgut. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Acbp5 in Genome Data Viewer
    Location:
    66D14-66D14; 3-26 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (8788144..8788545, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (8781244..8781645, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44527 Neighboring gene Formin homology 2 domain containing Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. New insights into the functions of ACBD4/5-like proteins using a combined phylogenetic and experimental approach across model organisms. Kors S, et al. Biochim Biophys Acta Mol Cell Res, 2024 Dec. PMID 39271061
    2. The ACBP gene family in Rhodnius prolixus: Expression, characterization and function of RpACBP-1. Majerowicz D, et al. Insect Biochem Mol Biol, 2016 May. PMID 27001070
    3. The Drosophila FHOD1-like formin Knittrig acts through Rok to promote stress fiber formation and directed macrophage migration during the cellular immune response. Lammel U, et al. Development, 2014 Mar. PMID 24553290
    4. A distinct Acyl-CoA binding protein (ACBP6) shapes tissue plasticity during nutrient adaptation in Drosophila. Li X, et al. Nat Commun, 2023 Nov 21. PMID 37989752, Free PMC Article
    5. Chronic circadian misalignment results in reduced longevity and large-scale changes in gene expression in Drosophila. Boomgarden AC, et al. BMC Genomics, 2019 Jan 7. PMID 30616504, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables fatty-acyl-CoA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables fatty-acyl-CoA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Acyl-CoA binding protein 5
    Names
    Acbp5-PA
    CG5804-PA
    acyl-CoA-binding protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      8788144..8788545 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139998.4 → NP_648255.1  Acyl-CoA binding protein 5 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648255.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VSP9
      Related
      FBpp0076318
      Conserved Domains (1) summary
      cl00221
      Location:2 → 76
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VSP9 Q9VSP9

    Gene LinkOut

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