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    PIG-F Phosphatidylinositol glycan anchor biosynthesis class F [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40139, updated on 9-Dec-2024

    Summary

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    Official Symbol
    PIG-Fprovided by FlyBase
    Official Full Name
    Phosphatidylinositol glycan anchor biosynthesis class Fprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036893
    Locus tag
    Dmel_CG9376
    See related
    AllianceGenome:FB:FBgn0036893
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9376; Dmel\CG9376; DmPIG-F
    Summary
    Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Is expressed in adult head and organism. Orthologous to human PIGF (phosphatidylinositol glycan anchor biosynthesis class F). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See PIG-F in Genome Data Viewer
    Location:
    76B9-76B9; 3-45 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19612455..19613489)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19605555..19606589)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene lush Neighboring gene uncharacterized protein Neighboring gene Lon protease Neighboring gene lethal (3) 76BDm Neighboring gene anti-silencing factor 1 Neighboring gene male sterile (3) 76Cc

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Nuclear envelope localization of PIG-B is essential for GPI-anchor synthesis in Drosophila. Yamamoto-Hino M, et al. J Cell Sci, 2018 Oct 26. PMID 30266758, Free PMC Article
    2. A computational and experimental approach toward a priori identification of alternatively spliced exons. Philipps DL, et al. RNA, 2004 Dec. PMID 15525709, Free PMC Article
    3. Identification of ER proteins involved in the functional organisation of the early secretory pathway in Drosophila cells by a targeted RNAi screen. Kondylis V, et al. PLoS One, 2011 Feb 23. PMID 21383842, Free PMC Article
    4. Variant-to-gene mapping followed by cross-species genetic screening identifies GPI-anchor biosynthesis as a regulator of sleep. Palermo J, et al. Sci Adv, 2023 Jan 6. PMID 36608130, Free PMC Article
    5. Heterochromatin protein 1 (HP1a) positively regulates euchromatic gene expression through RNA transcript association and interaction with hnRNPs in Drosophila. Piacentini L, et al. PLoS Genet, 2009 Oct. PMID 19798443, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in GPI anchor biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    phosphatidylinositol glycan anchor biosynthesis class F
    Names
    CG9376-PA
    PIG-F-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      19612455..19613489
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140877.4 → NP_649134.3  phosphatidylinositol glycan anchor biosynthesis class F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649134.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MTV3, Q9VW21
      Related
      FBpp0074714
      Conserved Domains (1) summary
      pfam06699
      Location:81 → 214
      PIG-F; GPI biosynthesis protein family Pig-F
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MTV3 Q8MTV3
    Q9VW21 Q9VW21

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