U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG2915 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35754, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG2915provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033241
    Locus tag
    Dmel_CG2915
    See related
    AllianceGenome:FB:FBgn0033241
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG2915
    Summary
    Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Located in vesicle. Is expressed in several structures, including adult head; anlage in statu nascendi; antennal anlage; antennal primordium; and head epidermis primordium. Human ortholog(s) of this gene implicated in chronic kidney disease. Orthologous to several human genes including CPA5 (carboxypeptidase A5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG2915 in Genome Data Viewer
    Location:
    43F7-43F8; 2-57 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (7958207..7960015, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (3845712..3847520, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ahuizotl Neighboring gene uncharacterized protein Neighboring gene Septin 5 Neighboring gene spenito Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genome-wide assessment of AU-rich elements by the AREScore algorithm. Spasic M, et al. PLoS Genet, 2012 Jan. PMID 22242014, Free PMC Article
    2. Genes encoding novel secreted and transmembrane proteins are temporally and spatially regulated during Drosophila melanogaster embryogenesis. Zúñiga A, et al. BMC Biol, 2009 Sep 22. PMID 19772636, Free PMC Article
    3. Identification of genes underlying hypoxia tolerance in Drosophila by a P-element screen. Azad P, et al. G3 (Bethesda), 2012 Oct. PMID 23050227, Free PMC Article
    4. Proteomic analysis of the Drosophila larval hemolymph clot. Karlsson C, et al. J Biol Chem, 2004 Dec 10. PMID 15466469
    5. Identification of genes expressed during Drosophila melanogaster gastrulation by using subtractive hybridization. González-Agüero M, et al. Gene, 2005 Jan 31. PMID 15716118

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables metallocarboxypeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metallocarboxypeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endomembrane system HDA PubMed 
    located_in extracellular region HDA PubMed 
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in vesicle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG2915-PA
    CG2915-PB
    NP_610338.1
    NP_724631.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      7958207..7960015 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136494.4 → NP_610338.1  uncharacterized protein Dmel_CG2915, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610338.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E9F9, Q86P95
      Related
      FBpp0087955
      Conserved Domains (3) summary
      cd03860
      Location:153 → 446
      M14_CP_A-B_like; Peptidase M14 carboxypeptidase subfamily A/B-like
      COG2866
      Location:50 → 433
      MpaA; Murein tripeptide amidase MpaA [Cell wall/membrane/envelope biogenesis]
      pfam02244
      Location:63 → 133
      Propep_M14; Carboxypeptidase activation peptide

    2. NM_165577.3 → NP_724631.1  uncharacterized protein Dmel_CG2915, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724631.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E9F9, Q86P95
      Related
      FBpp0087954
      Conserved Domains (3) summary
      cd03860
      Location:153 → 446
      M14_CP_A-B_like; Peptidase M14 carboxypeptidase subfamily A/B-like
      COG2866
      Location:50 → 433
      MpaA; Murein tripeptide amidase MpaA [Cell wall/membrane/envelope biogenesis]
      pfam02244
      Location:63 → 133
      Propep_M14; Carboxypeptidase activation peptide
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0E9F9 Q0E9F9
    Q86P95 Q86P95

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous