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    RpS2 Ribosomal protein S2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34309, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RpS2provided by FlyBase
    Official Full Name
    Ribosomal protein S2provided by FlyBase
    Primary source
    FLYBASE:FBgn0004867
    Locus tag
    Dmel_CG5920
    See related
    AllianceGenome:FB:FBgn0004867
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Posey202; CG5920; Dm01335; Dmel\CG5920; dS2; l(2)03848; l(2)k04603; Rp S2; rps2; rpS2; S2; S5; sop
    Summary
    A structural constituent of ribosome. Predicted to be involved in translation. Located in cytosolic ribosome and nucleolus. Colocalizes with nuclear chromosome. Is expressed in adult head; adult heart; nurse cell; organism; and ovary. Orthologous to human RPS2 (ribosomal protein S2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See RpS2 in Genome Data Viewer
    Location:
    30E1-30E1; 2-37 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (9896265..9897552, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (9896265..9897552, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene U snoRNA host gene 2 Neighboring gene Bekka Neighboring gene Mucin 30E Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning and analysis of the S2 ribosomal protein cDNA from Drosophila. Barrio R, et al. Nucleic Acids Res, 1993 Jan 25. PMID 8441641, Free PMC Article
    2. string of pearls encodes Drosophila ribosomal protein S2, has Minute-like characteristics, and is required during oogenesis. Cramton SE, et al. Genetics, 1994 Aug. PMID 7982558, Free PMC Article
    3. A spinosyn-sensitive Drosophila melanogaster nicotinic acetylcholine receptor identified through chemically induced target site resistance, resistance gene identification, and heterologous expression. Watson GB, et al. Insect Biochem Mol Biol, 2010 May. PMID 19944756
    4. Drosophila Low Temperature Viability Protein 1 (LTV1) Is Required for Ribosome Biogenesis and Cell Growth Downstream of Drosophila Myc (dMyc). Kim W, et al. J Biol Chem, 2015 May 22. PMID 25858587, Free PMC Article
    5. The Unfolded Protein Response Triggers Site-Specific Regulatory Ubiquitylation of 40S Ribosomal Proteins. Higgins R, et al. Mol Cell, 2015 Jul 2. PMID 26051182, Free PMC Article

    See all (101) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome HDA PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in cytoplasmic translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosolic ribosome HDA PubMed 
    located_in cytosolic ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    colocalizes_with nuclear chromosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of small ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal protein S2
    Names
    40S ribosomal protein S2
    CG5920-PA
    CG5920-PB
    CG5920-PC
    RpS2-PA
    RpS2-PB
    RpS2-PC
    S2 ribosomal protein
    ribosome RS2
    string of pearls

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      9896265..9897552 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298856.1 → NP_001285785.1  ribosomal protein S2, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285785.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P31009, Q9VL74
      UniProtKB/TrEMBL
      M9PB84
      Conserved Domains (1) summary
      PTZ00070
      Location:37 → 257
      PTZ00070; 40S ribosomal protein S2; Provisional

    2. NM_057526.5 → NP_476874.1  ribosomal protein S2, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476874.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P31009, Q9VL74
      UniProtKB/TrEMBL
      M9PB84
      Related
      FBpp0079500
      Conserved Domains (1) summary
      PTZ00070
      Location:37 → 257
      PTZ00070; 40S ribosomal protein S2; Provisional

    3. NM_001273374.2 → NP_001260303.1  ribosomal protein S2, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260303.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P31009, Q9VL74
      UniProtKB/TrEMBL
      M9PB84
      Conserved Domains (1) summary
      PTZ00070
      Location:37 → 257
      PTZ00070; 40S ribosomal protein S2; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PB84 M9PB84
    P31009.2 P31009

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