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    CG11141 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35672, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11141provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033177
    Locus tag
    Dmel_CG11141
    See related
    AllianceGenome:FB:FBgn0033177
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11141
    Summary
    Predicted to be involved in protein exit from endoplasmic reticulum. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 49. Orthologous to human TECPR2 (tectonin beta-propeller repeat containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11141 in Genome Data Viewer
    Location:
    43C3-43C3; 2-56 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (7459685..7463395, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (3347190..3350900, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45320 Neighboring gene myo-inositol-1-phosphate synthase Neighboring gene uncharacterized protein Neighboring gene p47

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Drosophila pigmentation gene pink (p) encodes a homologue of human Hermansky-Pudlak syndrome 5 (HPS5). Falcón-Pérez JM, et al. Traffic, 2007 Feb. PMID 17156100
    2. Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphology. Broderick NA, et al. mBio, 2014 May 27. PMID 24865556, Free PMC Article
    3. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article
    4. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in protein exit from endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11141-PA
    CG11141-PB
    CG11141-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      7459685..7463395 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299230.1 → NP_001286159.1  uncharacterized protein Dmel_CG11141, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286159.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6NLL1, Q6NMV3, Q960Z3
      UniProtKB/TrEMBL
      E2QC72
      Conserved Domains (1) summary
      sd00039
      Location:138 → 188
      7WD40; WD40 repeat [structural motif]

    2. NM_136438.4 → NP_610282.1  uncharacterized protein Dmel_CG11141, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610282.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6NLL1, Q6NMV3, Q960Z3
      UniProtKB/TrEMBL
      E2QC72
      Related
      FBpp0088070
      Conserved Domains (1) summary
      sd00039
      Location:138 → 188
      7WD40; WD40 repeat [structural motif]

    3. NM_165525.3 → NP_724559.1  uncharacterized protein Dmel_CG11141, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724559.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6NLL1, Q6NMV3, Q960Z3
      UniProtKB/TrEMBL
      E2QC72
      Related
      FBpp0088071
      Conserved Domains (1) summary
      sd00039
      Location:138 → 188
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E2QC72 E2QC72
    Q6NLL1.1 Q6NLL1

    Gene LinkOut

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