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    Nubp1 NUBP iron-sulfur cluster assembly factor 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35000, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nubp1provided by FlyBase
    Official Full Name
    NUBP iron-sulfur cluster assembly factor 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0032597
    Locus tag
    Dmel_CG17904
    See related
    AllianceGenome:FB:FBgn0032597
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG17904; Dmel\CG17904; Nbp35
    Summary
    Predicted to enable ATP hydrolysis activity and iron-sulfur cluster binding activity. Predicted to be involved in iron-sulfur cluster assembly. Predicted to be part of cytosolic [4Fe-4S] assembly scaffold complex. Predicted to be active in cytosol. Orthologous to human NUBP1 (NUBP iron-sulfur cluster assembly factor 1, cytosolic). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See Nubp1 in Genome Data Viewer
    Location:
    36A12-36A12; 2-52 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16732550..16733624)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16732550..16733624)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene tRNA splicing endonuclease subunit 2 Neighboring gene uncharacterized protein Neighboring gene Proteasome beta4 subunit Neighboring gene gluon Neighboring gene Chitin and LDLR binding deacetylase 3 Neighboring gene Like Sm 7 Neighboring gene Bub3 interacting GLEBS and Zinc finger domain protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables ATP-dependent FeS chaperone activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables iron-sulfur cluster binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables iron-sulfur cluster binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in iron-sulfur cluster assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in iron-sulfur cluster assembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in iron-sulfur cluster assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of cytosolic [4Fe-4S] assembly scaffold complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    NUBP iron-sulfur cluster assembly factor 1
    Names
    CG17904-PA
    Nubp1-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      16732550..16733624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135961.4NP_609805.1  NUBP iron-sulfur cluster assembly factor 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609805.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VJI9
      Related
      FBpp0080448
      Conserved Domains (2) summary
      COG0489
      Location:10282
      Mrp; Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster [Cell cycle control, cell division, chromosome partitioning]
      pfam10609
      Location:54307
      ParA; NUBPL iron-transfer P-loop NTPase