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    CG1951 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43423, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG1951provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039623
    Locus tag
    Dmel_CG1951
    See related
    AllianceGenome:FB:FBgn0039623
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG1951
    Summary
    Predicted to enable ATP binding activity. Involved in sexual reproduction. Is expressed in adult head. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita-4. Orthologous to human SCYL2 (SCY1 like pseudokinase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG1951 in Genome Data Viewer
    Location:
    98F5-98F5; 3-97 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29027236..29030938)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (24852958..24856660)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene eukaryotic translation initiation factor 4E6 Neighboring gene antisense RNA:CR45044 Neighboring gene Strictosidine synthase-like 2 Neighboring gene beta1,4-N-acetylgalactosaminyltransferase B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Effect of Common Inversion Polymorphisms In(2L)t and In(3R)Mo on Patterns of Transcriptional Variation in Drosophila melanogaster. Lavington E, et al. G3 (Bethesda), 2017 Nov 6. PMID 28916647, Free PMC Article
    2. Evaluation of the genomic extent of effects of fixed inversion differences on intraspecific variation and interspecific gene flow in Drosophila pseudoobscura and D. persimilis. Machado CA, et al. Genetics, 2007 Mar. PMID 17179068, Free PMC Article
    3. Classification of nonenzymatic homologues of protein kinases. Anamika K, et al. Comp Funct Genomics, 2009. PMID 19809514, Free PMC Article
    4. Evolutionary EST analysis identifies rapidly evolving male reproductive proteins in Drosophila. Swanson WJ, et al. Proc Natl Acad Sci U S A, 2001 Jun 19. PMID 11404480, Free PMC Article
    5. A modifier screen for Bazooka/PAR-3 interacting genes in the Drosophila embryo epithelium. Shao W, et al. PLoS One, 2010 Apr 1. PMID 20368978, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    NOT enables protein kinase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sexual reproduction IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG1951-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      29027236..29030938
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143398.4 → NP_651655.1  uncharacterized protein Dmel_CG1951 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651655.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VAR0
      Related
      FBpp0084711
      Conserved Domains (3) summary
      cd14011
      Location:37 → 316
      PK_SCY1_like; Pseudokinase domain of Scy1-like proteins
      pfam00069
      Location:31 → 314
      Pkinase; Protein kinase domain
      sd00044
      Location:396 → 425
      HEAT; HEAT repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VAR0 Q9VAR0

    Gene LinkOut

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