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    MICAL-like MICAL-like [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39475, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MICAL-likeprovided by FlyBase
    Official Full Name
    MICAL-likeprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036333
    Locus tag
    Dmel_CG11259
    See related
    AllianceGenome:FB:FBgn0036333
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    AAK93415; CG11259; Dmel\CG11259
    Summary
    Involved in endocytic recycling. Is active in terminal bouton. Is expressed in several structures, including Malpighian tubule primordium; embryonic epipharynx; embryonic/larval midgut primordium; epithelium; and gut section. Orthologous to several human genes including MICALL1 (MICAL like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See MICAL-like in Genome Data Viewer
    Location:
    69F5-69F5; 3-39 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (13011976..13015332, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (13005076..13008432, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene Cullin 6 Neighboring gene uncharacterized protein Neighboring gene mitochondrial ribosomal protein L20

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. MICAL-like Regulates Fasciclin II Membrane Cycling and Synaptic Development. Nahm M, et al. Mol Cells, 2016 Oct. PMID 27770767, Free PMC Article
    2. Calponin homology domains at a glance. Korenbaum E, et al. J Cell Sci, 2002 Sep 15. PMID 12186940
    3. Flying through the drosophila cytoskeletal genome. Goldstein LS, et al. J Cell Biol, 2000 Jul 24. PMID 10908588, Free PMC Article
    4. The Roles of the LIM Domain Proteins in Drosophila Cardiac and Hematopoietic Morphogenesis. She M, et al. Front Cardiovasc Med, 2021. PMID 33681304, Free PMC Article
    5. Burst of young retrogenes and independent retrogene formation in mammals. Pan D, et al. PLoS One, 2009. PMID 19325906, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in endocytic recycling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in terminal bouton IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    MICAL-like
    Names
    CG11259-PA
    MICAL-like-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      13011976..13015332 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140364.3 → NP_648621.1  MICAL-like [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648621.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q960L8, Q9VU34
      Related
      FBpp0075632
      Conserved Domains (3) summary
      cd09400
      Location:146 → 207
      LIM_like_1; LIM domain in proteins of unknown function
      pfam00307
      Location:14 → 111
      CH; Calponin homology (CH) domain
      pfam12130
      Location:778 → 933
      DUF3585; Protein of unknown function (DUF3585)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VU34 Q9VU34

    Gene LinkOut

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