U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    rseA anti-sigma E factor RseA [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 885196, updated on 11-Dec-2020

    Summary

    Go to the top of the page Help
    Gene symbol
    rseA
    Gene description
    anti-sigma E factor RseA
    Locus tag
    Rv1222
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000962.3 (1365344..1365808)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene methyltransferase Neighboring gene ECF RNA polymerase sigma factor SigE Neighboring gene serine protease HtrA Neighboring gene Sec-independent protein translocase protein TatB

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Assessing the role of Rv1222 (RseA) as an anti-sigma factor of the Mycobacterium tuberculosis extracytoplasmic sigma factor SigE. Boldrin F, et al. Sci Rep, 2019 Mar 14. PMID 30872756, Free PMC Article
    2. Novel mechanism of gene regulation: the protein Rv1222 of Mycobacterium tuberculosis inhibits transcription by anchoring the RNA polymerase onto DNA. Rudra P, et al. Nucleic Acids Res, 2015 Jul 13. PMID 25999340, Free PMC Article
    3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Assessing the role of Rv1222 (RseA) as an anti-sigma factor of the Mycobacterium tuberculosis extracytoplasmic sigma factor SigE.
      Title: Assessing the role of Rv1222 (RseA) as an anti-sigma factor of the Mycobacterium tuberculosis extracytoplasmic sigma factor SigE.
    2. The study demonstrates that the positively charged C-terminus tail of Rv1222 is responsible for anchoring RNA polymerase (RNAP)on DNA, hence the protein slows down the movement of RNAP along the DNA during transcription elongation.
      Title: Novel mechanism of gene regulation: the protein Rv1222 of Mycobacterium tuberculosis inhibits transcription by anchoring the RNA polymerase onto DNA.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    General protein information

    Go to the top of the page Help
    Preferred Names
    anti-sigma E factor RseA
    NP_215738.1
    • A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004 PMID:14766927).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      1365344..1365808
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_215738.1 anti-sigma E factor RseA [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_215738.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      L0T905
      UniProtKB/TrEMBL
      Q79FQ8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    L0T905.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials