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    epoxide hydrolase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855801, updated on 9-Dec-2024

    Summary

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    Official Full Name
    epoxide hydrolase
    Primary source
    SGD:S000005347
    Locus tag
    YNR064C
    See related
    AllianceGenome:SGD:S000005347; FungiDB:YNR064C; VEuPathDB:YNR064C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables epoxide hydrolase activity. Involved in epoxide metabolic process. Orthologous to human ABHD6 (abhydrolase domain containing 6, acylglycerol lipase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (749136..750008, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Pul3p Neighboring gene Pul4p Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Saccharomyces cerevisiae ORF YNR064c protein has characteristics of an 'orphaned' epoxide hydrolase. Elfström LT, et al. Biochim Biophys Acta, 2005 May 15. PMID 15769598
    2. A network of yeast basic helix-loop-helix interactions. Robinson KA, et al. Nucleic Acids Res, 2000 Nov 15. PMID 11071933, Free PMC Article
    3. The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications. Philippsen P, et al. Nature, 1997 May 29. PMID 9169873
    4. Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes. Fasolo J, et al. Genes Dev, 2011 Apr 1. PMID 21460040, Free PMC Article
    5. Systematic identification of genes involved in metabolic acid stress resistance in yeast and their potential as cancer targets. Shin JJ, et al. Dis Model Mech, 2016 Sep 1. PMID 27519690, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Saccharomyces cerevisiae ORF YNR064c protein has characteristics of an 'orphaned' epoxide hydrolase
      Title: The Saccharomyces cerevisiae ORF YNR064c protein has characteristics of an 'orphaned' epoxide hydrolase.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables carboxylic ester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables epoxide hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables epoxide hydrolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in epoxide metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    epoxide hydrolase
    NP_014462.1
    • Epoxide hydrolase; member of the alpha/beta hydrolase fold family; may have a role in detoxification of epoxides

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      749136..750008 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183241.1 → NP_014462.1  TPA: epoxide hydrolase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014462.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1N9, P53750
      UniProtKB/TrEMBL
      A6ZSD8, B3LPH9, B5VR89, C7GIY2, C8ZFU3
      Conserved Domains (1) summary
      pfam00561
      Location:30 → 275
      Abhydrolase_1; alpha/beta hydrolase fold
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53750.1

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