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    malS alpha-amylase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948088, updated on 3-Dec-2024

    Summary

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    Official Symbol
    malS
    Official Full Name
    alpha-amylase
    Primary source
    ECOCYC:EG11316
    Locus tag
    b3571
    See related
    ASAP:ABE-0011668
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3560
    Summary
    MalT regulon. [More information is available at EcoGene: EG11316]. MalS is a periplasmic enzyme that degrades linear dextrins of at least three glucose residues. [More information is available at EcoCyc: EG11316].
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    Genomic context

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    Sequence:
    NC_000913.3 (3737497..3739527)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional dual regulator XylR Neighboring gene putative glycoside hydrolase Bax Neighboring gene putative translational regulatory protein BaxL Neighboring gene valine--pyruvate aminotransferase Neighboring gene putative electron transport protein YsaA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Biochemical characterization and mass spectrometric disulfide bond mapping of periplasmic alpha-amylase MalS of Escherichia coli. Spiess C, et al. J Biol Chem, 1997 Aug 29. PMID 9268356
    2. Facilitated diffusion of p-nitrophenyl-alpha-D-maltohexaoside through the outer membrane of Escherichia coli. Characterization of LamB as a specific and saturable channel for maltooligosaccharides. Freundlieb S, et al. J Biol Chem, 1988 Jan 5. PMID 3275641
    3. Alpha-amylase of Escherichia coli, mapping and cloning of the structural gene, malS, and identification of its product as a periplasmic protein. Freundlieb S, et al. J Biol Chem, 1986 Feb 25. PMID 3005273
    4. Cloning and characterization of the Escherichia coli K-12 alanine-valine transaminase (avtA) gene. Wang MD, et al. J Bacteriol, 1987 Sep. PMID 3040683, Free PMC Article
    5. Molecular characterization of the MalT-dependent periplasmic alpha-amylase of Escherichia coli encoded by malS. Schneider E, et al. J Biol Chem, 1992 Mar 15. PMID 1544897

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on mature peptide
      Title: Molecular characterization of the MalT-dependent periplasmic alpha-amylase of Escherichia coli encoded by malS.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables alpha-amylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables alpha-amylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calcium ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, acting on glycosyl bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in alpha-glucan catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within alpha-glucan catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in oligosaccharide catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in outer membrane-bounded periplasmic space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in periplasmic space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in periplasmic space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    alpha-amylase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3737497..3739527
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418028.1 alpha-amylase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418028.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q5RLZ2
      Conserved Domains (1) summary
      PRK09505
      Location:1 → 676
      malS; alpha-amylase; Reviewed
    Nucleotide Protein
    Heading Accession and Version

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