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    ybdG miniconductance mechanosensitive channel YbdG [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946243, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ybdG
    Official Full Name
    miniconductance mechanosensitive channel YbdG
    Primary source
    ECOCYC:G6323
    Locus tag
    b0577
    See related
    ASAP:ABE-0001978
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0569
    Summary
    mscS, kefA, yjeP, ybiO, ybdG and ynaI are paralogs. [More information is available at EcoGene: EG12620]. Sequence analysis has identified YbdG as a member of the small mechanosensitive ion channel (MscS) family of proteins. [More information is available at EcoCyc: G6323].
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    Genomic context

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    Sequence:
    NC_000913.3 (603416..604663, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene copper/silver export system RND permease Neighboring gene phenylalanine:H(+) symporter PheP Neighboring gene NAD(P)H-dependent nitroreductase NfsB Neighboring gene PF04237 family protein YbdF

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The mechanosensitive channel YbdG from Escherichia coli has a role in adaptation to osmotic up-shock. Amemiya S, et al. J Biol Chem, 2019 Aug 16. PMID 31256002, Free PMC Article
    2. Multiple mechanosensitive ion channels from Escherichia coli, activated at different thresholds of applied pressure. Berrier C, et al. J Membr Biol, 1996 May. PMID 8661505
    3. Physical characterisation of the Escherichia coli B gene encoding nitroreductase and its over-expression in Escherichia coli K12. Michael NP, et al. FEMS Microbiol Lett, 1994 Dec 1. PMID 7813889
    4. YbdG in Escherichia coli is a threshold-setting mechanosensitive channel with MscM activity. Schumann U, et al. Proc Natl Acad Sci U S A, 2010 Jul 13. PMID 20616037, Free PMC Article
    5. Comparison of SDS- and methanol-assisted protein solubilization and digestion methods for Escherichia coli membrane proteome analysis by 2-D LC-MS/MS. Zhang N, et al. Proteomics, 2007 Feb. PMID 17309111

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables mechanosensitive monoatomic ion channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mechanosensitive monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mechanosensitive monoatomic ion channel activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to osmotic stress IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cellular response to osmotic stress IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cellular response to osmotic stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to osmotic stress IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    miniconductance mechanosensitive channel YbdG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      603416..604663 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415109.1 miniconductance mechanosensitive channel YbdG [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415109.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FRB8, A0A8T6QCL8
      Conserved Domains (1) summary
      pfam00924
      Location:144 → 396
      MS_channel; Mechanosensitive ion channel
    Nucleotide Protein
    Heading Accession and Version

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