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    yafN antitoxin YafN [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944920, updated on 3-Dec-2024

    Summary

    Official Symbol
    yafN
    Official Full Name
    antitoxin YafN
    Primary source
    ECOCYC:G6116
    Locus tag
    b0232
    See related
    ASAP:ABE-0000793
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0233
    Summary
    YafN is an StbD homolog and a distant homolog of DnaT. [More information is available at EcoGene: EG13151]. Polar dinB mutations affecting the dinB-yafN-yafO-yafP operon reduce spontaneous mutagenesis . [More information is available at EcoCyc: G6116].
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    Genomic context

    Sequence:
    NC_000913.3 (252005..252298)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene DNA polymerase IV Neighboring gene ribosome-dependent mRNA interferase toxin YafO Neighboring gene putative N-acetyltransferase YafP

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in SOS response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in SOS response NAS
    Non-traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of DNA-templated transcription NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in regulation of growth NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of toxin-antitoxin complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      252005..252298
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414767.1 antitoxin YafN [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414767.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5C9AAI8
      Conserved Domains (1) summary
      PRK09778
      Location:197
      PRK09778; type I toxin-antitoxin system antitoxin YafN