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    sufD Fe-S cluster scaffold complex subunit SufD [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944878, updated on 3-Dec-2024

    Summary

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    Official Symbol
    sufD
    Official Full Name
    Fe-S cluster scaffold complex subunit SufD
    Primary source
    ECOCYC:G6907
    Locus tag
    b1681
    See related
    ASAP:ABE-0005617
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1677; ynhC
    Summary
    SufB and SufD are homologous. [More information is available at EcoGene: EG13963]. The SufB-SufC-SufD complex activates the cysteine desulfurase activity SufS in conjunction with the SufE sulfur acceptor protein . [More information is available at EcoCyc: G6907].
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    Genomic context

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    Sequence:
    NC_000913.3 (1760520..1761791, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene L,D-transpeptidase LdtE Neighboring gene sulfur carrier protein SufE Neighboring gene L-cysteine desulfurase Neighboring gene Fe-S cluster scaffold complex subunit SufC Neighboring gene Fe-S cluster scaffold complex subunit SufB Neighboring gene iron-sulfur cluster insertion protein SufA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular dynamism of Fe-S cluster biosynthesis implicated by the structure of the SufC(2)-SufD(2) complex. Wada K, et al. J Mol Biol, 2009 Mar 20. PMID 19361433, Free PMC Article
    2. Iron-sulfur (Fe-S) cluster assembly: the SufBCD complex is a new type of Fe-S scaffold with a flavin redox cofactor. Wollers S, et al. J Biol Chem, 2010 Jul 23. PMID 20460376, Free PMC Article
    3. The SufBCD Fe-S scaffold complex interacts with SufA for Fe-S cluster transfer. Chahal HK, et al. Biochemistry, 2009 Nov 10. PMID 19810706, Free PMC Article
    4. The SufE protein and the SufBCD complex enhance SufS cysteine desulfurase activity as part of a sulfur transfer pathway for Fe-S cluster assembly in Escherichia coli. Outten FW, et al. J Biol Chem, 2003 Nov 14. PMID 12941942
    5. Induction of the sufA operon encoding Fe-S assembly proteins by superoxide generators and hydrogen peroxide: involvement of OxyR, IHF and an unidentified oxidant-responsive factor. Lee JH, et al. Mol Microbiol, 2004 Mar. PMID 15009899

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within iron-sulfur cluster assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in iron-sulfur cluster assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within iron-sulfur cluster assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in iron-sulfur cluster assembly NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of iron-sulfur cluster assembly complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of iron-sulfur cluster assembly complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Fe-S cluster scaffold complex subunit SufD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1760520..1761791 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416196.1 Fe-S cluster scaffold complex subunit SufD [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416196.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6N8NLL4
      Conserved Domains (1) summary
      PRK10948
      Location:1 → 423
      PRK10948; Fe-S cluster assembly protein SufD
    Nucleotide Protein
    Heading Accession and Version

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