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    epmB lysine 2,3-aminomutase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948662, updated on 3-Dec-2024

    Summary

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    Official Symbol
    epmB
    Official Full Name
    lysine 2,3-aminomutase
    Primary source
    ECOCYC:G7836
    Locus tag
    b4146
    See related
    ASAP:ABE-0013580
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4140; yjeK
    Summary
    YjeK is a homolog of Clostridium subterminale KamA lysine 2,3-aminomutase activity, but its specific activity is only 0.1% of that of KamA, which may indicate the physiological substrate for YjeK is still unknown (Behshad, 2006). [More information is available at EcoGene: EG12473]. The yjeK gene product is similar to the lysine 2,3-aminomutase of Clostridium subterminale. [More information is available at EcoCyc: G7836].
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    Genomic context

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    Sequence:
    NC_000913.3 (4374629..4375657, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF4156 domain-containing lipoprotein YjeI Neighboring gene protein YjeJ Neighboring gene protein chain elongation factor EF-P Neighboring gene entericidin A lipoprotein, antidote to entericidin B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Enantiomeric free radicals and enzymatic control of stereochemistry in a radical mechanism: the case of lysine 2,3-aminomutases. Behshad E, et al. Biochemistry, 2006 Oct 24. PMID 17042480, Free PMC Article
    2. Predicting the pathway involved in post-translational modification of elongation factor P in a subset of bacterial species. Bailly M, et al. Biol Direct, 2010 Jan 13. PMID 20070887, Free PMC Article
    3. Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes. Burland V, et al. Nucleic Acids Res, 1995 Jun 25. PMID 7610040, Free PMC Article
    4. The binary protein-protein interaction landscape of Escherichia coli. Rajagopala SV, et al. Nat Biotechnol, 2014 Mar. PMID 24561554, Free PMC Article
    5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 4 iron, 4 sulfur cluster binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables intramolecular aminotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables intramolecular aminotransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within post-translational protein modification RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lysine 2,3-aminomutase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4374629..4375657 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418570.1 lysine 2,3-aminomutase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418570.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376MEZ0
      Conserved Domains (1) summary
      TIGR03821
      Location:15 → 335
      EFP_modif_epmB; EF-P beta-lysylation protein EpmB
    Nucleotide Protein
    Heading Accession and Version

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