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    RPL20A ribosomal 60S subunit protein L20A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855283, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RPL20A
    Official Full Name
    ribosomal 60S subunit protein L20A
    Primary source
    SGD:S000004855
    Locus tag
    YMR242C
    See related
    AllianceGenome:SGD:S000004855; FungiDB:YMR242C; VEuPathDB:YMR242C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RPL18A2
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Orthologous to human RPL18A (ribosomal protein L18a). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RPL20A in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    2
    Sequence:
    Chromosome: XIII; NC_001145.3 (753225..754220, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene U2 snRNP complex subunit CUS1 Neighboring gene Yhm2p Neighboring gene uncharacterized protein Neighboring gene Zn(2+) transporter ZRC1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Deletion of a subgroup of ribosome-related genes minimizes hypoxia-induced changes and confers hypoxia tolerance. Shah AN, et al. Physiol Genomics, 2011 Jul 27. PMID 21586670, Free PMC Article
    2. Use of a genome-wide approach to identify new genes that control resistance of Saccharomyces cerevisiae to ionizing radiation. Game JC, et al. Radiat Res, 2003 Jul. PMID 12816519
    3. Proteomic Analysis Identifies Ribosome Reduction as an Effective Proteotoxic Stress Response. Guerra-Moreno A, et al. J Biol Chem, 2015 Dec 11. PMID 26491016, Free PMC Article
    4. Farnesol inhibits translation to limit growth and filamentation in C. albicans and S. cerevisiae. Egbe NE, et al. Microb Cell, 2017 Sep 4. PMID 28913344, Free PMC Article
    5. Saccharomyces cerevisiae porin pore forms complexes with mitochondrial outer membrane proteins Om14p and Om45p. Lauffer S, et al. J Biol Chem, 2012 May 18. PMID 22461620, Free PMC Article

    See all (103) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IC
    Inferred by Curator
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 60S subunit protein L20A
    NP_013969.3
    • Ribosomal 60S subunit protein L20A; homologous to mammalian ribosomal protein L18A, no bacterial homolog; RPL20A has a paralog, RPL20B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      753225..754220 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182749.1 → NP_013969.3  TPA: ribosomal 60S subunit protein L20A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013969.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A1YV95, A1YV96, D6W068, P0C2I0, P0C2I1, P0CX23, P0CX24, P47913
      UniProtKB/TrEMBL
      A6ZPE7, B3LJX6, C8ZFA7, G2WNH8
      Conserved Domains (1) summary
      COG2157
      Location:66 → 151
      RPL20A; Ribosomal protein L20A (L18A) [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0CX23.1
    P0CX24.1

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