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    GSM1 Gsm1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853341, updated on 9-Dec-2024

    Summary

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    Official Symbol
    GSM1
    Official Full Name
    Gsm1p
    Primary source
    SGD:S000003639
    Locus tag
    YJL103C
    See related
    AllianceGenome:SGD:S000003639; FungiDB:YJL103C; VEuPathDB:YJL103C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables DNA-binding transcription factor activity. Involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See GSM1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (229025..230881, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene import motor complex subunit PAM16 Neighboring gene ncRNA Neighboring gene Mef2p Neighboring gene tRNA-Arg

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Computationally analyzing the possible biological function of YJL103C--an ORF potentially involved in the regulation of energy process in yeast. Deng Y, et al. Int J Mol Med, 2005 Jan. PMID 15583838
    2. Improved genome-wide localization by ChIP-chip using double-round T7 RNA polymerase-based amplification. van Bakel H, et al. Nucleic Acids Res, 2008 Mar. PMID 18180247, Free PMC Article
    3. Linking DNA-binding proteins to their recognition sequences by using protein microarrays. Ho SW, et al. Proc Natl Acad Sci U S A, 2006 Jun 27. PMID 16785442, Free PMC Article
    4. Yeast zinc cluster transcription factors involved in the switch from fermentation to respiration show interdependency for DNA binding revealing a novel type of DNA recognition. Martinez KP, et al. Nucleic Acids Res, 2024 Mar 21. PMID 38109318, Free PMC Article
    5. GSM1 Requires Hap4 for Expression and Plays a Role in Gluconeogenesis and Utilization of Nonfermentable Carbon Sources. Bhondeley M, et al. Genes (Basel), 2024 Aug 27. PMID 39336719, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding HDA PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to starvation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IC
    Inferred by Curator
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Gsm1p
    NP_012432.1
    • Putative zinc cluster hypothetical protein; proposed to be involved in the regulation of energy metabolism, based on patterns of expression and sequence analysis

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      229025..230881 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181536.1 → NP_012432.1  TPA: Gsm1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012432.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3LQ10, C8ZBB1, D6VW81, P42950, Q66R68
      Conserved Domains (1) summary
      smart00066
      Location:14 → 44
      GAL4; GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P42950.1

    Gene LinkOut

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