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    [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853443, updated on 9-Dec-2024

    Summary

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    Primary source
    SGD:S000006625
    Locus tag
    YNCJ0018W
    See related
    AllianceGenome:SGD:S000006625
    Gene type
    tRNA
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables triplet codon-amino acid adaptor activity. Involved in mitochondrial translation. Located in cytosol and mitochondrion. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: X
    Sequence:
    Chromosome: X; NC_001142.9 (414966..415038)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Vtc4p Neighboring gene DNA-directed RNA polymerase III subunit RPC17 Neighboring gene tRNA-Trp Neighboring gene RNA-binding RNA processing protein NOP9

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mechanisms of tRNA import into yeast mitochondria: an overview. Tarassov IA, et al. Biochimie, 1996. PMID 8915539
    2. Import of nuclear deoxyribonucleic acid coded lysine-accepting transfer ribonucleic acid (anticodon C-U-U) into yeast mitochondria. Martin RP, et al. Biochemistry, 1979 Oct 16. PMID 387075
    3. Evidence for an adaptation mechanism of mitochondrial translation via tRNA import from the cytosol. Kamenski P, et al. Mol Cell, 2007 Jun 8. PMID 17560369
    4. Thio-Modification of tRNA at the Wobble Position as Regulator of the Kinetics of Decoding and Translocation on the Ribosome. Ranjan N, et al. J Am Chem Soc, 2017 Apr 26. PMID 28368583
    5. tRNA genes and retroelements in the yeast genome. Hani J, et al. Nucleic Acids Res, 1998 Feb 1. PMID 9443958, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    • Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE analysis; a small portion is imported into mitochondria via interaction with mt lysyl-tRNA synthetase Msk1p and is necessary to decode AAG codons at high temperature, when base modification of mt-encoded tRNA-Lys is reduced

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables triplet codon-amino acid adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables triplet codon-amino acid adaptor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables triplet codon-amino acid adaptor activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translational elongation IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

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