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    MTC3 Mtc3p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852626, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MTC3
    Official Full Name
    Mtc3p
    Primary source
    SGD:S000003195
    Locus tag
    YGL226W
    See related
    AllianceGenome:SGD:S000003195; FungiDB:YGL226W; VEuPathDB:YGL226W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrion. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MTC3 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (73340..73711)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene glucose-induced degradation complex subunit VID30 Neighboring gene dolichyl-diphosphooligosaccharide--protein glycotransferase subunit Neighboring gene tRNA-Val Neighboring gene GDP-mannose transporter

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of cytochrome c oxidase activity by modulation of the catalytic site. Schäfer J, et al. Sci Rep, 2018 Jul 30. PMID 30061583, Free PMC Article
    2. Overexpression screens identify conserved dosage chromosome instability genes in yeast and human cancer. Duffy S, et al. Proc Natl Acad Sci U S A, 2016 Sep 6. PMID 27551064, Free PMC Article
    3. Multiple pathways influence mitochondrial inheritance in budding yeast. Frederick RL, et al. Genetics, 2008 Feb. PMID 18245340, Free PMC Article
    4. Synchronized assembly of the oxidative phosphorylation system controls mitochondrial respiration in yeast. Moretti-Horten DN, et al. Dev Cell, 2024 Apr 22. PMID 38508182
    5. Functional genomics analysis of the Saccharomyces cerevisiae iron responsive transcription factor Aft1 reveals iron-independent functions. Berthelet S, et al. Genetics, 2010 Jul. PMID 20439772, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in mitochondrial electron transport, cytochrome c to oxygen IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial electron transport, cytochrome c to oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of respiratory chain complex IV IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of respiratory chain complex IV IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Mtc3p
    NP_011289.1
    • hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; mtc3 is synthetically sick with cdc13-1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      73340..73711
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181092.1 → NP_011289.1  TPA: Mtc3p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011289.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVA9, P53077
      UniProtKB/TrEMBL
      G2WDN4
      Conserved Domains (1) summary
      cl02792
      Location:25 → 109
      Cyt_c_Oxidase_IV; Cytochrome c oxidase subunit IV. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53077.1

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