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    ERV15 Erv15p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852511, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ERV15
    Official Full Name
    Erv15p
    Primary source
    SGD:S000000414
    Locus tag
    YBR210W
    See related
    AllianceGenome:SGD:S000000414; FungiDB:YBR210W; VEuPathDB:YBR210W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable signaling receptor binding activity. Involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in COPII-coated ER to Golgi transport vesicle. Orthologous to several human genes including CNIH4 (cornichon family member 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ERV15 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (645550..645978)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene tRNA-Cys Neighboring gene tRNA-Glu Neighboring gene Ame1p Neighboring gene Ngr1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transport of axl2p depends on erv14p, an ER-vesicle protein related to the Drosophila cornichon gene product. Powers J, et al. J Cell Biol, 1998 Sep 7. PMID 9732282, Free PMC Article
    2. Sec24 is a coincidence detector that simultaneously binds two signals to drive ER export. Pagant S, et al. Curr Biol, 2015 Feb 16. PMID 25619760, Free PMC Article
    3. Erv14 family cargo receptors are necessary for ER exit during sporulation in Saccharomyces cerevisiae. Nakanishi H, et al. J Cell Sci, 2007 Mar 1. PMID 17298976
    4. Characteristics of endoplasmic reticulum-derived transport vesicles. Rexach MF, et al. J Cell Biol, 1994 Sep. PMID 8063853, Free PMC Article
    5. A Slowed Cell Cycle Stabilizes the Budding Yeast Genome. Vinton PJ, et al. Genetics, 2017 Jun. PMID 28468908, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in COPII-coated ER to Golgi transport vesicle IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Erv15p
    NP_009769.1
    • Protein involved in export of proteins from the endoplasmic reticulum; ERV15 has a paralog, ERV14, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      645550..645978
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178558.1 → NP_009769.1  TPA: Erv15p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009769.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQK6, P38312
      UniProtKB/TrEMBL
      A6ZLF0, B3LMV0, C7GUY2, D3UEV7, G2W9L3, N1PAV1
      Conserved Domains (1) summary
      pfam03311
      Location:8 → 120
      Cornichon; Cornichon protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38312.1

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