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    GSR1 Gsr1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855341, updated on 9-Dec-2024

    Summary

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    Official Symbol
    GSR1
    Official Full Name
    Gsr1p
    Primary source
    SGD:S000004910
    Locus tag
    YMR295C
    See related
    AllianceGenome:SGD:S000004910; FungiDB:YMR295C; VEuPathDB:YMR295C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Acts upstream of or within regulation of cell wall (1->3)-beta-D-glucan biosynthetic process. Located in several cellular components, including cellular bud neck; cellular bud tip; and mating projection tip. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See GSR1 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (858297..858890, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene glutamyl-tRNA(Gln) amidotransferase subunit HER2 Neighboring gene Jnm1p Neighboring gene serine C-palmitoyltransferase LCB1 Neighboring gene carboxypeptidase C PRC1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Proteome-scale movements and compartment connectivity during the eukaryotic cell cycle. Litsios A, et al. Cell, 2024 Mar 14. PMID 38452761,
    2. Identification of Novel Components of Target-of-Rapamycin Signaling Pathway by Network-Based Multi-Omics Integrative Analysis. Dereli Eke E, et al. OMICS, 2019 May. PMID 30985253
    3. Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiae. Chen Y, et al. Mol Cancer Res, 2005 Dec. PMID 16380504
    4. Nonsense-mediated mRNA decay involves two distinct Upf1-bound complexes. Dehecq M, et al. EMBO J, 2018 Nov 2. PMID 30275269, Free PMC Article
    5. Reverse recruitment: the Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation. Menon BB, et al. Proc Natl Acad Sci U S A, 2005 Apr 19. PMID 15817685, Free PMC Article

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of cell wall (1->3)-beta-D-glucan biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of cell wall (1->3)-beta-D-glucan biosynthetic process IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in cellular bud HDA PubMed 
    located_in cellular bud neck HDA PubMed 
    located_in cellular bud tip HDA PubMed 
    located_in mating projection tip HDA PubMed 

    General protein information

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    Preferred Names
    Gsr1p
    NP_014024.1
    • Putative regulator of 1,3-beta-glucan biosynthesis; interacts with the catalytic (Fks1p and Gsc2p) and regulatory subunits (Rho1p) of 1,3-beta-glucan synthase; has a negative genetic interaction with RHO1; localizes to the cell periphery during early G1, to the bud tip in late G1, to the bud at S/G2, to the periphery of the bud at metaphase and at the bud neck during telophase; periodically expressed during the cell cycle; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      858297..858890 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182804.1 → NP_014024.1  TPA: Gsr1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014024.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0C2, Q03559
      UniProtKB/TrEMBL
      A6ZN11, B5VQ62, C7GTK4, C8ZFG4, G2WL04, N1P626
      Conserved Domains (1) summary
      pfam10295
      Location:49 → 116
      DUF2406; Uncharacterized protein (DUF2406)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03559.1

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