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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001253912.2 → NP_001240841.1 TBC1 domain family member 1 isoform 2
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) has multiple differences in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
- Source sequence(s)
-
AK074954, AK295746, AW364769, BC050321, BQ672157, CR996632, DB036208
- Consensus CDS
-
CCDS58897.1
- UniProtKB/Swiss-Prot
-
Q86TI0
- UniProtKB/TrEMBL
-
Q8NC59
- Related
- ENSP00000423651.1, ENST00000508802.5
- Conserved Domains (5) summary
-
- smart00164
Location:891 → 1028
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- cd00934
Location:21 → 150
- PTB; Phosphotyrosine-binding (PTB) PH-like fold
- cd01269
Location:164 → 371
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam09786
Location:543 → 838
- CytochromB561_N; Cytochrome B561, N terminal
- pfam11830
Location:789 → 839
- DUF3350; Domain of unknown function (DUF3350)
-
NM_001253913.2 → NP_001240842.1 TBC1 domain family member 1 isoform 3
See identical proteins and their annotated locations for NP_001240842.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR, lacks a large portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. Variants 3 and 4 encode the same isoform (3), which has a significantly shorter N-terminus, compared to isoform 1.
- Source sequence(s)
-
AC098680, AC108933, AK057182, AK074954, AW364769
- UniProtKB/TrEMBL
-
Q8NC59
- Conserved Domains (2) summary
-
- smart00164
Location:2 → 111
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- COG1196
Location:146 → 246
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
-
NM_001253914.2 → NP_001240843.1 TBC1 domain family member 1 isoform 3
See identical proteins and their annotated locations for NP_001240843.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR, lacks a large portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. Variants 3 and 4 encode the same isoform (3), which has a significantly shorter N-terminus, compared to isoform 1.
- Source sequence(s)
-
AK074954, CR996632
- UniProtKB/TrEMBL
-
Q8NC59
- Related
-
ENST00000407365.5
- Conserved Domains (2) summary
-
- smart00164
Location:2 → 111
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- COG1196
Location:146 → 246
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
-
NM_001253915.2 → NP_001240844.1 TBC1 domain family member 1 isoform 4
Status: VALIDATED
- Description
- Transcript Variant: This variant (5) differs in the 5' UTR, lacks a large portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (4) has a significantly shorter N-terminus, compared to isoform 1.
- Source sequence(s)
-
AK074954, BC032337, CR996632
- UniProtKB/TrEMBL
-
Q8NC59
-
NM_001396959.1 → NP_001383888.1 TBC1 domain family member 1 isoform 5
Status: VALIDATED
- Source sequence(s)
-
AC021106, AC098680, AC108933
- Consensus CDS
-
CCDS93491.1
- UniProtKB/TrEMBL
-
A0A8V8TNS9
- Related
- ENSP00000513987.1, ENST00000698857.1
- Conserved Domains (5) summary
-
- smart00164
Location:891 → 1108
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- COG1196
Location:1131 → 1241
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00934
Location:21 → 150
- PTB; Phosphotyrosine-binding (PTB) PH-like fold
- cd01269
Location:164 → 371
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam11830
Location:784 → 839
- DUF3350; Domain of unknown function (DUF3350)
-
NM_015173.4 → NP_055988.2 TBC1 domain family member 1 isoform 1
See identical proteins and their annotated locations for NP_055988.2
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AB449881, AK074954, BC014529, BC050321, DB036208
- Consensus CDS
-
CCDS33972.1
- UniProtKB/Swiss-Prot
- B7Z3D9, E9PGH8, Q86TI0, Q96K82, Q9UPP4
- UniProtKB/TrEMBL
-
B9A6J6
- Related
- ENSP00000261439.4, ENST00000261439.9
- Conserved Domains (4) summary
-
- smart00164
Location:797 → 1014
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- cd00934
Location:21 → 150
- PTB; Phosphotyrosine-binding (PTB) PH-like fold
- cd01269
Location:164 → 371
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam11830
Location:695 → 745
- DUF3350; Domain of unknown function (DUF3350)
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000004.12 Reference GRCh38.p14 Primary Assembly
- Range
-
37891084..38139173
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011513659.3 → XP_011511961.1 TBC1 domain family member 1 isoform X1
- Conserved Domains (5) summary
-
- smart00164
Location:924 → 1141
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- cd00934
Location:21 → 150
- PTB; Phosphotyrosine-binding (PTB) PH-like fold
- cd01269
Location:164 → 391
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam09786
Location:563 → 871
- CytochromB561_N; Cytochrome B561, N terminal
- pfam11830
Location:822 → 872
- DUF3350; Domain of unknown function (DUF3350)
-
XM_011513660.4 → XP_011511962.1 TBC1 domain family member 1 isoform X2
- Conserved Domains (5) summary
-
- smart00164
Location:911 → 1128
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- cd00934
Location:21 → 150
- PTB; Phosphotyrosine-binding (PTB) PH-like fold
- cd01269
Location:164 → 391
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam09786
Location:563 → 858
- CytochromB561_N; Cytochrome B561, N terminal
- pfam11830
Location:809 → 859
- DUF3350; Domain of unknown function (DUF3350)
-
XM_011513662.4 → XP_011511964.1 TBC1 domain family member 1 isoform X4
- Conserved Domains (4) summary
-
- smart00164
Location:884 → 1101
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- cd00934
Location:21 → 150
- PTB; Phosphotyrosine-binding (PTB) PH-like fold
- cd01269
Location:164 → 391
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam11830
Location:782 → 832
- DUF3350; Domain of unknown function (DUF3350)
-
XM_011513663.4 → XP_011511965.1 TBC1 domain family member 1 isoform X5
- Conserved Domains (4) summary
-
- smart00164
Location:871 → 1088
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- cd00934
Location:21 → 150
- PTB; Phosphotyrosine-binding (PTB) PH-like fold
- cd01269
Location:164 → 391
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam11830
Location:769 → 819
- DUF3350; Domain of unknown function (DUF3350)
-
XM_011513664.4 → XP_011511966.1 TBC1 domain family member 1 isoform X6
- Conserved Domains (4) summary
-
- smart00164
Location:870 → 1087
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- cd00934
Location:21 → 150
- PTB; Phosphotyrosine-binding (PTB) PH-like fold
- cd01269
Location:164 → 391
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam11830
Location:768 → 818
- DUF3350; Domain of unknown function (DUF3350)
-
XM_017007918.3 → XP_016863407.1 TBC1 domain family member 1 isoform X8
-
XM_011513665.4 → XP_011511967.1 TBC1 domain family member 1 isoform X11
- Conserved Domains (4) summary
-
- smart00164
Location:830 → 1047
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- cd00934
Location:21 → 150
- PTB; Phosphotyrosine-binding (PTB) PH-like fold
- cd01269
Location:164 → 391
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam11830
Location:728 → 778
- DUF3350; Domain of unknown function (DUF3350)
-
XM_011513666.4 → XP_011511968.1 TBC1 domain family member 1 isoform X12
- Conserved Domains (4) summary
-
- smart00164
Location:817 → 1034
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- cd00934
Location:21 → 150
- PTB; Phosphotyrosine-binding (PTB) PH-like fold
- cd01269
Location:164 → 391
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam11830
Location:715 → 765
- DUF3350; Domain of unknown function (DUF3350)
-
XM_005262646.4 → XP_005262703.1 TBC1 domain family member 1 isoform X3
See identical proteins and their annotated locations for XP_005262703.1
- Conserved Domains (5) summary
-
- smart00164
Location:904 → 1121
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- COG1196
Location:1144 → 1254
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00934
Location:21 → 150
- PTB; Phosphotyrosine-binding (PTB) PH-like fold
- cd01269
Location:164 → 371
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam11830
Location:797 → 852
- DUF3350; Domain of unknown function (DUF3350)
-
XM_047449888.1 → XP_047305844.1 TBC1 domain family member 1 isoform X7
-
XM_017007919.3 → XP_016863408.1 TBC1 domain family member 1 isoform X9
-
XM_047449889.1 → XP_047305845.1 TBC1 domain family member 1 isoform X10
-
XM_017007920.3 → XP_016863409.1 TBC1 domain family member 1 isoform X13
- Conserved Domains (4) summary
-
- smart00164
Location:810 → 1027
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- COG1196
Location:1050 → 1160
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00934
Location:21 → 150
- PTB; Phosphotyrosine-binding (PTB) PH-like fold
- cd01269
Location:164 → 371
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
-
XM_011513668.3 → XP_011511970.1 TBC1 domain family member 1 isoform X24
- Conserved Domains (2) summary
-
- cd00934
Location:21 → 150
- PTB; Phosphotyrosine-binding (PTB) PH-like fold
- cd01269
Location:164 → 391
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
-
XM_047449890.1 → XP_047305846.1 TBC1 domain family member 1 isoform X14
- UniProtKB/Swiss-Prot
- B7Z3D9, E9PGH8, Q86TI0, Q96K82, Q9UPP4
- UniProtKB/TrEMBL
-
B9A6J6
-
XM_047449897.1 → XP_047305853.1 TBC1 domain family member 1 isoform X22
- UniProtKB/TrEMBL
-
Q6PJJ8
- Related
- ENSP00000421641.3, ENST00000510573.6
-
XM_047449891.1 → XP_047305847.1 TBC1 domain family member 1 isoform X15
-
XM_005262649.4 → XP_005262706.1 TBC1 domain family member 1 isoform X16
- Conserved Domains (4) summary
-
- smart00164
Location:775 → 992
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- cd01269
Location:35 → 242
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam09786
Location:414 → 722
- CytochromB561_N; Cytochrome B561, N terminal
- pfam11830
Location:673 → 723
- DUF3350; Domain of unknown function (DUF3350)
-
XM_047449892.1 → XP_047305848.1 TBC1 domain family member 1 isoform X17
-
XM_047449893.1 → XP_047305849.1 TBC1 domain family member 1 isoform X18
- UniProtKB/TrEMBL
-
Q6PJJ8
-
XM_047449894.1 → XP_047305850.1 TBC1 domain family member 1 isoform X19
- UniProtKB/TrEMBL
-
Q6PJJ8
-
XM_047449895.1 → XP_047305851.1 TBC1 domain family member 1 isoform X20
- UniProtKB/TrEMBL
-
Q6PJJ8
- Related
-
ENST00000698858.1
-
XM_047449896.1 → XP_047305852.1 TBC1 domain family member 1 isoform X21
- UniProtKB/TrEMBL
-
Q6PJJ8
-
XM_017007921.3 → XP_016863410.1 TBC1 domain family member 1 isoform X23
- UniProtKB/TrEMBL
-
Q6PJJ8
-
XM_011513670.4 → XP_011511972.1 TBC1 domain family member 1 isoform X25
- UniProtKB/TrEMBL
-
A0JNU9
- Conserved Domains (2) summary
-
- smart00164
Location:123 → 340
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- pfam11830
Location:21 → 71
- DUF3350; Domain of unknown function (DUF3350)
-
XM_047449898.1 → XP_047305854.1 TBC1 domain family member 1 isoform X26
- UniProtKB/TrEMBL
-
Q8NC59
Alternate T2T-CHM13v2.0
Genomic
-
NC_060928.1 Alternate T2T-CHM13v2.0
- Range
-
37860161..38108248
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054349390.1 → XP_054205365.1 TBC1 domain family member 1 isoform X1
-
XM_054349391.1 → XP_054205366.1 TBC1 domain family member 1 isoform X2
-
XM_054349393.1 → XP_054205368.1 TBC1 domain family member 1 isoform X4
-
XM_054349394.1 → XP_054205369.1 TBC1 domain family member 1 isoform X5
-
XM_054349395.1 → XP_054205370.1 TBC1 domain family member 1 isoform X6
-
XM_054349397.1 → XP_054205372.1 TBC1 domain family member 1 isoform X8
-
XM_054349400.1 → XP_054205375.1 TBC1 domain family member 1 isoform X11
-
XM_054349401.1 → XP_054205376.1 TBC1 domain family member 1 isoform X12
-
XM_054349392.1 → XP_054205367.1 TBC1 domain family member 1 isoform X3
-
XM_054349396.1 → XP_054205371.1 TBC1 domain family member 1 isoform X7
-
XM_054349398.1 → XP_054205373.1 TBC1 domain family member 1 isoform X9
-
XM_054349399.1 → XP_054205374.1 TBC1 domain family member 1 isoform X10
-
XM_054349402.1 → XP_054205377.1 TBC1 domain family member 1 isoform X13
-
XM_054349411.1 → XP_054205386.1 TBC1 domain family member 1 isoform X24
-
XM_054349403.1 → XP_054205378.1 TBC1 domain family member 1 isoform X14
- UniProtKB/Swiss-Prot
- B7Z3D9, E9PGH8, Q86TI0, Q96K82, Q9UPP4
- UniProtKB/TrEMBL
-
B9A6J6
-
XM_054349404.1 → XP_054205379.1 TBC1 domain family member 1 isoform X16
-
XM_054349405.1 → XP_054205380.1 TBC1 domain family member 1 isoform X17
-
XM_054349406.1 → XP_054205381.1 TBC1 domain family member 1 isoform X18
- UniProtKB/TrEMBL
-
Q6PJJ8
-
XM_054349407.1 → XP_054205382.1 TBC1 domain family member 1 isoform X19
- UniProtKB/TrEMBL
-
Q6PJJ8
-
XM_054349408.1 → XP_054205383.1 TBC1 domain family member 1 isoform X20
- UniProtKB/TrEMBL
-
Q6PJJ8
-
XM_054349409.1 → XP_054205384.1 TBC1 domain family member 1 isoform X21
- UniProtKB/TrEMBL
-
Q6PJJ8
-
XM_054349410.1 → XP_054205385.1 TBC1 domain family member 1 isoform X23
- UniProtKB/TrEMBL
-
Q6PJJ8
-
XM_054349412.1 → XP_054205387.1 TBC1 domain family member 1 isoform X25
- UniProtKB/TrEMBL
-
A0JNU9
-
XM_054349413.1 → XP_054205388.1 TBC1 domain family member 1 isoform X26
- UniProtKB/TrEMBL
-
Q8NC59