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    SUL2 sulfate permease [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850781, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SUL2
    Official Full Name
    sulfate permease
    Primary source
    SGD:S000004082
    Locus tag
    YLR092W
    See related
    AllianceGenome:SGD:S000004082; FungiDB:YLR092W; VEuPathDB:YLR092W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables sulfate transmembrane transporter activity. Involved in sulfate transmembrane transport. Located in plasma membrane. Orthologous to human SLC26A11 (solute carrier family 26 member 11). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SUL2 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (323544..326225)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Xdj1p Neighboring gene Gep5p Neighboring gene Nyv1p Neighboring gene Gis3p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sulfate transport mutants affect hydrogen sulfide and sulfite production during alcoholic fermentation. Walker ME, et al. Yeast, 2021 Jun. PMID 33560525
    2. Chromate causes sulfur starvation in yeast. Pereira Y, et al. Toxicol Sci, 2008 Dec. PMID 18794233
    3. Differential paralog divergence modulates genome evolution across yeast species. Sanchez MR, et al. PLoS Genet, 2017 Feb. PMID 28196070, Free PMC Article
    4. Inactivation of Saccharomyces cerevisiae sulfate transporter Sul2p: use it and lose it. Jennings ML, et al. Biophys J, 2012 Feb 22. PMID 22385847, Free PMC Article
    5. Sul1 and Sul2 sulfate transceptors signal to protein kinase A upon exit of sulfur starvation. Kankipati HN, et al. J Biol Chem, 2015 Apr 17. PMID 25724649, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables secondary active sulfate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sulfate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sulfate transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in chloride transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sulfate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sulfate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sulfate transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane HDA PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sulfate permease
    NP_013193.1
    • High affinity sulfate permease; sulfate uptake is mediated by specific sulfate transporters Sul1p and Sul2p, which control the concentration of endogenous activated sulfate intermediates

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      323544..326225
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181979.1 → NP_013193.1  TPA: sulfate permease [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013193.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VY92, Q12325
      UniProtKB/TrEMBL
      A7A0Z6
      Conserved Domains (1) summary
      COG0659
      Location:118 → 827
      SUL1; Sulfate permease or related transporter, MFS superfamily [Inorganic ion transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12325.1

    Gene LinkOut

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