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    JIP5 Jip5p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856298, updated on 9-Dec-2024

    Summary

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    Official Symbol
    JIP5
    Official Full Name
    Jip5p
    Primary source
    SGD:S000006373
    Locus tag
    YPR169W
    See related
    AllianceGenome:SGD:S000006373; FungiDB:YPR169W; VEuPathDB:YPR169W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in ribosomal large subunit biogenesis. Located in nucleolus. Orthologous to human WDR55 (WD repeat domain 55). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See JIP5 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (878690..880168)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene phosphoadenylyl-sulfate reductase (thioredoxin) Neighboring gene mediator complex subunit NUT2 Neighboring gene tRNA-Ile Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Assessing systems properties of yeast mitochondria through an interaction map of the organelle. Perocchi F, et al. PLoS Genet, 2006 Oct 20. PMID 17054397, Free PMC Article
    2. The jmjN and jmjC domains of the yeast zinc finger protein Gis1 interact with 19 proteins involved in transcription, sumoylation and DNA repair. Tronnersjö S, et al. Mol Genet Genomics, 2007 Jan. PMID 17043893
    3. The RNA helicase Dbp10 coordinates assembly factor association with PTC maturation during ribosome biogenesis. Mitterer V, et al. Nucleic Acids Res, 2024 Feb 28. PMID 38113283, Free PMC Article
    4. Rational extension of the ribosome biogenesis pathway using network-guided genetics. Li Z, et al. PLoS Biol, 2009 Oct. PMID 19806183, Free PMC Article
    5. Viewing pre-60S maturation at a minute's timescale. Zisser G, et al. Nucleic Acids Res, 2018 Apr 6. PMID 29294095, Free PMC Article

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in ribosomal large subunit biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleolus HDA PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Jip5p
    NP_015495.2
    • Protein required for biogenesis of the large ribosomal subunit; required for biogenesis of the large ribosomal subunit; interacts with proteins involved in RNA processing, ribosome biogenesis, ubiquitination and demethylation; similar to WDR55, a human WD repeat protein; essential gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      878690..880168
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184266.1 → NP_015495.2  TPA: Jip5p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015495.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W4H0, Q06214
      UniProtKB/TrEMBL
      B3LKD0, C7GP52
      Conserved Domains (2) summary
      COG2319
      Location:114 → 417
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:132 → 168
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06214.2

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