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    CG14694 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41307, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG14694provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037845
    Locus tag
    Dmel_CG14694
    See related
    AllianceGenome:FB:FBgn0037845
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG14694
    Summary
    Predicted to enable thiamine transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including abdominal aortic aneurysm; biotin-responsive basal ganglia disease; cleft lip; dextro-looped transposition of the great arteries; and megaloblastic anemia. Orthologous to several human genes including SLC19A1 (solute carrier family 19 member 1) and SLC19A2 (solute carrier family 19 member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See CG14694 in Genome Data Viewer
    Location:
    86C7-86C7; 3-50 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (10858202..10859813, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (6683924..6685535, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Selenoprotein R

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables thiamine transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables vitamin transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in vitamin transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG14694-PA

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      10858202..10859813 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141771.3NP_650028.1  uncharacterized protein Dmel_CG14694 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650028.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VGV6
      Related
      FBpp0081774
      Conserved Domains (1) summary
      pfam01770
      Location:2411
      Folate_carrier; Reduced folate carrier