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    Cyt-c1L Cytochrome c1-like [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43457, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cyt-c1Lprovided by FlyBase
    Official Full Name
    Cytochrome c1-likeprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039651
    Locus tag
    Dmel_CG14508
    See related
    AllianceGenome:FB:FBgn0039651
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14508; CY1; cyt-c1L; CytC1L; Dmel\CG14508
    Summary
    Predicted to enable ubiquinol-cytochrome-c reductase activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be part of respiratory chain complex III. Is expressed in adult head; spermatozoon; wing hinge primordium; and wing pouch. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 6. Orthologous to human CYC1 (cytochrome c1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Cyt-c1L in Genome Data Viewer
    Location:
    99A1-99A1; 3-98 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29202660..29204133, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25028382..25029855, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Metazoan SpoT homolog-1 Neighboring gene long non-coding RNA::CR31044 Neighboring gene mir-279 stem loop Neighboring gene mir-996 stem loop

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables electron transfer activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquinol-cytochrome-c reductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of respiratory chain complex III IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of respiratory chain complex III ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    cytochrome c1-like
    Names
    CG14508-PA
    Cyt-c1L-PA
    Ubiquinol-cytochrome c reductase cytochrome C1, heme protein
    cytochrome c1, heme protein, mitochondrial
    NP_651683.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      29202660..29204133 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143426.3NP_651683.1  cytochrome c1-like [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651683.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VAM8
      Related
      FBpp0084775
      Conserved Domains (2) summary
      COG2857
      Location:73300
      CYT1; Cytochrome c1 [Energy production and conversion]
      pfam02167
      Location:80299
      Cytochrom_C1; Cytochrome C1 family