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    Exo84 Exocyst 84 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43163, updated on 9-Dec-2024

    Summary

    Official Symbol
    Exo84provided by FlyBase
    Official Full Name
    Exocyst 84provided by FlyBase
    Primary source
    FLYBASE:FBgn0266668
    Locus tag
    Dmel_CG6095
    See related
    AllianceGenome:FB:FBgn0266668
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0153538.55; CG6095; DExo84; Dmel\CG6095; exo84; Exo84p; onr
    Summary
    Involved in several processes, including cytoskeleton-dependent cytokinesis; endocytic recycling; and maintenance of epithelial cell apical/basal polarity. Part of exocyst. Is expressed in adult head. Orthologous to human EXOC8 (exocyst complex component 8). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Exo84 in Genome Data Viewer
    Location:
    96F10-96F10; 3-89 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (26049731..26052257, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21875453..21877979, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Enhancer of split m7, helix-loop-helix Neighboring gene Enhancer of split m8, helix-loop-helix Neighboring gene groucho Neighboring gene Vacuolar protein sorting 2 Neighboring gene Cytidine/uridine monophosphate kinase 1

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi to plasma membrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in actomyosin contractile ring contraction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in endocytic recycling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in establishment or maintenance of cell polarity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in exocytosis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in maintenance of epithelial cell apical/basal polarity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in meiosis I cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in meiosis II cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in meiotic spindle organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neurotransmitter secretion NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in protein localization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein localization to plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in spermatid development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in synaptic vesicle docking NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in synaptic vesicle targeting NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in vesicle-mediated transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of exocyst IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of exocyst IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of exocyst IEA
    Inferred from Electronic Annotation
    more info
     
    part_of exocyst ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    part_of exocyst NAS
    Non-traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    exocyst 84
    Names
    CG6095-PA
    CG6095-PB
    Exo84 ortholog
    Exo84-PA
    Exo84-PB
    onion ring
    onion rings

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      26049731..26052257 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143197.2NP_651454.1  exocyst 84, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651454.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H1UUJ5, Q9VBI4
      Related
      FBpp0084350
      Conserved Domains (5) summary
      cd01226
      Location:131241
      PH_RalBD_exo84; Exocyst complex 84-kDa subunit Ral-binding domain/Pleckstrin Homology (PH) domain
      pfam00169
      Location:141233
      PH; PH domain
      pfam05177
      Location:224292
      RCSD; RCSD region
      pfam08700
      Location:489
      Vps51; Vps51/Vps67
      pfam16528
      Location:284484
      Exo84_C; Exocyst component 84 C-terminal
    2. NM_206576.2NP_996299.1  exocyst 84, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996299.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H1UUJ5, Q7KRZ3
      Conserved Domains (5) summary
      cd01226
      Location:132242
      PH_RalBD_exo84; Exocyst complex 84-kDa subunit Ral-binding domain/Pleckstrin Homology (PH) domain
      pfam00169
      Location:142234
      PH; PH domain
      pfam05177
      Location:225293
      RCSD; RCSD region
      pfam08700
      Location:490
      Vps51; Vps51/Vps67
      pfam16528
      Location:285485
      Exo84_C; Exocyst component 84 C-terminal