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    CG12259 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43347, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12259provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039557
    Locus tag
    Dmel_CG12259
    See related
    AllianceGenome:FB:FBgn0039557
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12259
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in chromatin organization. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in organism. Human ortholog(s) of this gene implicated in Armfield syndrome. Orthologous to human FAM50A (family with sequence similarity 50 member A) and FAM50B (family with sequence similarity 50 member B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12259 in Genome Data Viewer
    Location:
    98B6-98B6; 3-94 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (27919844..27921089, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (23745566..23746811, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene milkah Neighboring gene uncharacterized protein Neighboring gene mitochondrial ribosomal protein S22 Neighboring gene Buddy of Hmr 1 Neighboring gene BCAS2 Neighboring gene ncRNA Neighboring gene Ribosomal protein L4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulatory network in heat stress response in parasitoid wasp focusing on Xap5 heat stress regulator. Xiong S, et al. iScience, 2024 Jan 19. PMID 38205256, Free PMC Article
    2. Whole transcriptome screening for novel genes involved in meiosis and fertility in Drosophila melanogaster. Sun S, et al. Sci Rep, 2024 Feb 13. PMID 38351116, Free PMC Article
    3. Border cell polarity and collective migration require the spliceosome component Cactin. Miao G, et al. J Cell Biol, 2022 Jul 4. PMID 35612426, Free PMC Article
    4. Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach. Pazos Obregón F, et al. BMC Genomics, 2015 Sep 15. PMID 26370122, Free PMC Article
    5. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12259-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      27919844..27921089 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143338.3 → NP_651595.1  uncharacterized protein Dmel_CG12259 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651595.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VAY7
      Related
      FBpp0084639
      Conserved Domains (1) summary
      pfam04921
      Location:110 → 351
      XAP5; XAP5, circadian clock regulator
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VAY7.1 Q9VAY7

    Gene LinkOut

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