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    Lcp65Af Lcp65Af [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 45017, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lcp65Afprovided by FlyBase
    Official Full Name
    Lcp65Afprovided by FlyBase
    Primary source
    FLYBASE:FBgn0020639
    Locus tag
    Dmel_CG10533
    See related
    AllianceGenome:FB:FBgn0020639
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10533; DCP7; DmelLcp65Af; Dmel\CG10533; DMLCP65f; Lcp-f; LCP-f2
    Summary
    Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in chitin-based cuticle development. Predicted to be active in chitin-based extracellular matrix. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Lcp65Af in Genome Data Viewer
    Location:
    65A6-65A6; 3-16 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6136215..6136791, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6129315..6129891, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Lcp65Ag2 Neighboring gene Lcp65Ag1 Neighboring gene Lcp65Ae Neighboring gene Cuticular protein 65Av

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Is beta-pleated sheet the molecular conformation which dictates formation of helicoidal cuticle? Iconomidou VA, et al. Insect Biochem Mol Biol, 1999 Mar. PMID 10319442
    2. A cluster of cuticle protein genes of Drosophila melanogaster at 65A: sequence, structure and evolution. Charles JP, et al. Genetics, 1997 Nov. PMID 9383064, Free PMC Article
    3. Identification of proteins and developmental expression of RNAs encoded by the 65A cuticle protein gene cluster in Drosophila melanogaster. Charles JP, et al. Insect Biochem Mol Biol, 1998 Mar. PMID 9654737
    4. "What You Need, Baby, I Got It": Transposable Elements as Suppliers of Cis-Operating Sequences in Drosophila. Moschetti R, et al. Biology (Basel), 2020 Feb 3. PMID 32028630, Free PMC Article
    5. Imaginal discs secrete insulin-like peptide 8 to mediate plasticity of growth and maturation. Garelli A, et al. Science, 2012 May 4. PMID 22556250

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of chitin-based larval cuticle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of chitin-based larval cuticle ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables structural constituent of chitin-based larval cuticle ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chitin-based cuticle development ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in chitin-based extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in chitin-based extracellular matrix ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Lcp65Af
    Names
    CG10533-PA
    Lcp65Af-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      6136215..6136791 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057926.3 → NP_477274.1  Lcp65Af [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477274.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      P92194
      Related
      FBpp0076765
      Conserved Domains (1) summary
      pfam00379
      Location:32 → 87
      Chitin_bind_4; Insect cuticle protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P92194 P92194

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