U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG31091 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318591, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG31091provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051091
    Locus tag
    Dmel_CG31091
    See related
    AllianceGenome:FB:FBgn0051091
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5990; Dmel\CG31091
    Summary
    Predicted to enable triacylglycerol lipase activity. Predicted to be involved in lipid metabolic process. Is expressed in organism. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 8. Orthologous to human LIPK (lipase family member K); LIPM (lipase family member M); and LIPN (lipase family member N). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG31091 in Genome Data Viewer
    Location:
    96F7-96F7; 3-89 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25899903..25902172)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21725625..21727894)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Sodesque Neighboring gene Multicopper oxidase 3 Neighboring gene antisense RNA:CR43259 Neighboring gene uncharacterized protein Neighboring gene kin of rumpel Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Altered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagia. Subramanian M, et al. Dis Model Mech, 2013 May. PMID 23471909, Free PMC Article
    2. Drosophila melanogaster positive transcriptional elongation factors regulate metabolic and sex-biased expression in adults. Yang H, et al. BMC Genomics, 2017 May 18. PMID 28521739, Free PMC Article
    3. Drosophila type IV collagen mutation associates with immune system activation and intestinal dysfunction. Kiss M, et al. Matrix Biol, 2016 Jan. PMID 26363084
    4. The genomic basis of copper tolerance in Drosophila is shaped by a complex interplay of regulatory and environmental factors. Green L, et al. BMC Biol, 2022 Dec 8. PMID 36482348, Free PMC Article
    5. The DHR96 nuclear receptor controls triacylglycerol homeostasis in Drosophila. Sieber MH, et al. Cell Metab, 2009 Dec. PMID 19945405, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables hydrolase activity, acting on ester bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables triacylglycerol lipase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG31091-PB
    CG31091-PC
    NP_001247307.1
    NP_733127.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25899903..25902172
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_170248.3 → NP_733127.1  uncharacterized protein Dmel_CG31091, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733127.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IMS3
      Related
      FBpp0310536
      Conserved Domains (3) summary
      PLN02872
      Location:42 → 416
      PLN02872; triacylglycerol lipase
      pfam04083
      Location:55 → 117
      Abhydro_lipase; Partial alpha/beta-hydrolase lipase region
      pfam12695
      Location:104 → 239
      Abhydrolase_5; Alpha/beta hydrolase family

    2. NM_001260378.1 → NP_001247307.1  uncharacterized protein Dmel_CG31091, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247307.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IMS3
      Conserved Domains (3) summary
      PLN02872
      Location:42 → 416
      PLN02872; triacylglycerol lipase
      pfam04083
      Location:55 → 117
      Abhydro_lipase; Partial alpha/beta-hydrolase lipase region
      pfam12695
      Location:104 → 239
      Abhydrolase_5; Alpha/beta hydrolase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IMS3 Q8IMS3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools