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    Lcp9 Larval cuticle protein 9 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37963, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lcp9provided by FlyBase
    Official Full Name
    Larval cuticle protein 9provided by FlyBase
    Primary source
    FLYBASE:FBgn0025578
    Locus tag
    Dmel_CG16914
    See related
    AllianceGenome:FB:FBgn0025578
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG16914; DmelLcp9; Dmel\CG16914; lcp9; LCP9; LCPX
    Summary
    Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in chitin-based cuticle development. Predicted to be active in chitin-based extracellular matrix. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Lcp9 in Genome Data Viewer
    Location:
    60E1-60E1; 2-107 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24779979..24780428, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20667502..20667951, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Epidermal growth factor receptor pathway substrate clone 15 Neighboring gene antisense RNA:CR44067 Neighboring gene eggless Neighboring gene uncharacterized protein Neighboring gene Tyrosyl-tRNA synthetase, mitochondrial Neighboring gene uncharacterized protein Neighboring gene kenny

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Insect cuticular proteins. Andersen SO, et al. Insect Biochem Mol Biol, 1995 Feb. PMID 7711748
    2. Smoothened antagonist sonidegib affects the development of D. melanogaster larvae via suppression of epidermis formation. Jiang Z, et al. Pestic Biochem Physiol, 2023 Aug. PMID 37532307
    3. Identification of proteins and developmental expression of RNAs encoded by the 65A cuticle protein gene cluster in Drosophila melanogaster. Charles JP, et al. Insect Biochem Mol Biol, 1998 Mar. PMID 9654737
    4. Transcriptional Correlates of Chronic Alcohol Neuroadaptation in Drosophila Larvae. Anqueira-González A, et al. Front Behav Neurosci, 2021. PMID 34803626, Free PMC Article
    5. Transcriptome analysis provides insights for understanding the adverse effects of endosulfan in Drosophila melanogaster. Sharma A, et al. Chemosphere, 2011 Jan. PMID 21036383

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of chitin-based larval cuticle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of chitin-based larval cuticle ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables structural constituent of chitin-based larval cuticle NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chitin-based cuticle development ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    involved_in larval chitin-based cuticle development NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in chitin-based extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in chitin-based extracellular matrix ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in extracellular region NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    larval cuticle protein 9
    Names
    CG16914-PA
    Lcp9-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24779979..24780428 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079130.2 → NP_523854.1  larval cuticle protein 9 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523854.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P82384, Q9W109
      UniProtKB/TrEMBL
      D0IQB8
      Conserved Domains (1) summary
      pfam00379
      Location:34 → 85
      Chitin_bind_4; Insect cuticle protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P82384.2 P82384

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