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    CG11456 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40309, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11456provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037031
    Locus tag
    Dmel_CG11456
    See related
    AllianceGenome:FB:FBgn0037031
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11456
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including central brain primordium; ganglia; germline cell; gonad; and ventral nerve cord primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11456 in Genome Data Viewer
    Location:
    77F1-77F1; 3-47 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (20841987..20844340)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (20835087..20837440)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR45943 Neighboring gene uncharacterized protein Neighboring gene COP9 signalosome subunit 3 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44686 Neighboring gene Seminal fluid protein 77F

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genomics of Recombination Rate Variation in Temperature-Evolved Drosophila melanogaster Populations. Winbush A, et al. Genome Biol Evol, 2021 Jan 7. PMID 33247719, Free PMC Article
    2. A Comprehensive Drosophila melanogaster Transcription Factor Interactome. Shokri L, et al. Cell Rep, 2019 Apr 16. PMID 30995488, Free PMC Article
    3. A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development. Schertel C, et al. Genome Res, 2015 Apr. PMID 25568052, Free PMC Article
    4. Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. Leung W, et al. G3 (Bethesda), 2015 Mar 4. PMID 25740935, Free PMC Article
    5. Transcriptional regulators form diverse groups with context-dependent regulatory functions. Stampfel G, et al. Nature, 2015 Dec 3. PMID 26550828

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11456-PA
    CG11456-PB
    CG11456-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      20841987..20844340
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001170013.2 → NP_001163484.1  uncharacterized protein Dmel_CG11456, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163484.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NL58
      Conserved Domains (1) summary
      sd00017
      Location:232 → 253
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. NM_141008.2 → NP_649265.1  uncharacterized protein Dmel_CG11456, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649265.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VPA2
      Related
      FBpp0077922
      Conserved Domains (1) summary
      sd00017
      Location:232 → 253
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. NM_001275201.1 → NP_001262130.1  uncharacterized protein Dmel_CG11456, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262130.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VPA2
      Conserved Domains (1) summary
      sd00017
      Location:232 → 253
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6NL58 Q6NL58
    Q9VPA2 Q9VPA2

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