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    CCT2 Chaperonin containing TCP1 subunit 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31838, updated on 9-Dec-2024

    Summary

    Official Symbol
    CCT2provided by FlyBase
    Official Full Name
    Chaperonin containing TCP1 subunit 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0030086
    Locus tag
    Dmel_CG7033
    See related
    AllianceGenome:FB:FBgn0030086
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cct2; Cct2; CG7033; Dmel\CG7033; Q8IRM8_DROME; Q9W392_DROME; SD02216p; TCP-1beta; Tcp1-beta; TCP1-beta; TCP1beta
    Summary
    Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Located in cytoplasm. Is expressed in several structures, including adult head; adult heart; embryonic anal pad; embryonic/larval midgut primordium; and gut section. Used to study candidiasis. Orthologous to human CCT2 (chaperonin containing TCP1 subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See CCT2 in Genome Data Viewer
    Location:
    8C8-8C8; 1-26 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (9089513..9092826)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (8983546..8986859)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene mir-13b-2 stem loop Neighboring gene uncharacterized protein Neighboring gene Bx42

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP-dependent protein folding chaperone IEA
    Inferred from Electronic Annotation
    more info
     
    enables unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of chaperonin-containing T-complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of chaperonin-containing T-complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm HDA PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    chaperonin containing TCP1 subunit 2
    Names
    CCT2-PA
    CG7033-PA
    TCP-1 subunit 2beta

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      9089513..9092826
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132296.3NP_572524.1  chaperonin containing TCP1 subunit 2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572524.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95TI2, Q9W392
      Related
      FBpp0071226
      Conserved Domains (2) summary
      PTZ00212
      Location:1530
      PTZ00212; T-complex protein 1 subunit beta; Provisional
      cd03336
      Location:10527
      TCP1_beta; TCP-1 (CTT or eukaryotic type II) chaperonin family, beta subunit. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings. In contrast to bacterial group I chaperonins (GroEL) ...