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    Kaz Katazuke [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 326135, updated on 9-Dec-2024

    Summary

    Official Symbol
    Kazprovided by FlyBase
    Official Full Name
    Katazukeprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051357
    Locus tag
    Dmel_CG31357
    See related
    AllianceGenome:FB:FBgn0051357
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13638; CG31357; Dmel\CG31357
    Summary
    Predicted to contribute to ubiquitin protein ligase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of GID complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including central brain primordium; embryonic/larval midgut; embryonic/larval midgut interstitial cell; embryonic/larval midgut primordium; and ganglia. Orthologous to human MAEA (macrophage erythroblast attacher, E3 ubiquitin ligase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See Kaz in Genome Data Viewer
    Location:
    96A24-96A24; 3-85 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24828279..24829959, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20654001..20655681, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene nimA-like kinase Neighboring gene long non-coding RNA:CR43166 Neighboring gene RabX4 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45216 Neighboring gene sosie

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to ubiquitin protein ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    contributes_to ubiquitin-protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of GID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    katazuke
    Names
    CG31357-PA
    Kaz-PA

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      24828279..24829959 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_170171.2NP_733044.1  katazuke [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733044.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MSB1
      Related
      FBpp0084110
      Conserved Domains (4) summary
      smart00667
      Location:119150
      LisH; Lissencephaly type-1-like homology motif
      smart00668
      Location:158215
      CTLH; C-terminal to LisH motif
      smart00757
      Location:215302
      CRA; CT11-RanBPM
      pfam10607
      Location:158300
      CLTH; CTLH/CRA C-terminal to LisH motif domain