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    t-Grip128 testis-specific gamma-tubulin ring protein 128 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 317930, updated on 4-Jan-2025

    Summary

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    Official Symbol
    t-Grip128provided by FlyBase
    Official Full Name
    testis-specific gamma-tubulin ring protein 128provided by FlyBase
    Primary source
    FLYBASE:FBgn0052232
    Locus tag
    Dmel_CG32232
    See related
    AllianceGenome:FB:FBgn0052232
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG32232; Dmel\CG32232
    Summary
    Enables gamma-tubulin binding activity. Predicted to be involved in meiotic cell cycle; microtubule cytoskeleton organization; and mitotic cell cycle. Located in centriole. Is active in cytosol. [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See t-Grip128 in Genome Data Viewer
    Location:
    64C4-64C4; 3-13 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4993950..4996877, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4993950..4996877, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Connectin Neighboring gene long non-coding RNA:CR45685 Neighboring gene uncharacterized protein Neighboring gene ATP synthase, coupling factor 6-like Neighboring gene long non-coding RNA:CR43884

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Microtubule Organizing Centers Contain Testis-Specific γ-TuRC Proteins in Spermatids of Drosophila. Alzyoud E, et al. Front Cell Dev Biol, 2021. PMID 34660584, Free PMC Article
    2. Versatile gamma-tubulin complexes contribute to the dynamic organization of MTOCs during Drosophila spermatogenesis. Alzyoud E, et al. Commun Biol, 2024 Oct 24. PMID 39448788, Free PMC Article
    3. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
    4. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848
    5. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables gamma-tubulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables gamma-tubulin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    contributes_to microtubule minus-end binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic microtubule organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in meiotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule nucleation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in centriole IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of gamma-tubulin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    testis-specific gamma-tubulin ring protein 128
    Names
    CG32232-PA
    t-Grip128-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      4993950..4996877 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168109.1 → NP_729045.1  testis-specific gamma-tubulin ring protein 128 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729045.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IRA1
      Related
      FBpp0073229, FBtr0073373
      Conserved Domains (1) summary
      pfam04130
      Location:382 → 559
      Spc97_Spc98; Spc97 / Spc98 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IRA1 Q8IRA1

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