Miox Myo-inositol oxygenase [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Mioxprovided by FlyBase
Official Full Name: Myo-inositol oxygenaseprovided by FlyBase
Primary source: FLYBASE:FBgn0036262
Locus tag: Dmel_CG6910
See related: AllianceGenome:FB:FBgn0036262
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG6910; Dmel\CG6910; MIOX
Summary: Enables inositol oxygenase activity. Predicted to be involved in inositol catabolic process. Predicted to be located in cytoplasm. Is expressed in cardiogenic mesoderm; embryonic/larval fat body; fat body/gonad primordium; and trunk mesoderm. Orthologous to human MIOX (myo-inositol oxygenase). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 69A1-69A1; 3-38 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (12184984..12187860)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (12178084..12180960)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Homology

NCBI Orthologs

Orthologs from OrthoDB

mobile_element

Loc: 12187580-12187654 mobile_element_type = transposon:Rt1a{}5155

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
enables inositol oxygenase activity	IBA Inferred from Biological aspect of Ancestor more info
enables inositol oxygenase activity	IEA Inferred from Electronic Annotation more info
enables inositol oxygenase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables iron ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in inositol catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in inositol catabolic process	IEA Inferred from Electronic Annotation more info
involved_in inositol catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info

General protein information

Go to the top of the page Help

Preferred Names: Myo-inositol oxygenase

Names: CG6910-PB; CG6910-PC; Miox-PB; Miox-PC; myo-inositol oxygenase

NP_001261748.1

EC 1.13.99.1

NP_648556.3

EC 1.13.99.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_037436.4 Reference assembly

Range

12184984..12187860

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001274819.1 → NP_001261748.1 Myo-inositol oxygenase, isoform C [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001261748.1

Status: REVIEWED

UniProtKB/TrEMBL

M9PI33

Conserved Domains (1) summary

pfam05153
Location:27 → 275

MIOX; Myo-inositol oxygenase
NM_140299.3 → NP_648556.3 Myo-inositol oxygenase, isoform B [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_648556.3

Status: REVIEWED

UniProtKB/TrEMBL

Q6NMY0, Q9VTU9

Conserved Domains (1) summary

pfam05153
Location:44 → 292

MIOX; Myo-inositol oxygenase