U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Etfb Electron transfer flavoprotein beta subunit [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43515, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Etfbprovided by FlyBase
    Official Full Name
    Electron transfer flavoprotein beta subunitprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039697
    Locus tag
    Dmel_CG7834
    See related
    AllianceGenome:FB:FBgn0039697
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG 7834; CG7834; Dmel\CG7834; ETFB; Q0KHZ6
    Summary
    Predicted to enable electron transfer activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase. Located in mitochondrion. Is expressed in several structures, including adult head; adult heart; dorsal pharyngeal muscle cell; embryonic/larval midgut primordium; and gut section. Human ortholog(s) of this gene implicated in multiple acyl-CoA dehydrogenase deficiency. Orthologous to human ETFB (electron transfer flavoprotein subunit beta). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Etfb in Genome Data Viewer
    Location:
    99C1-99C1; 3-99 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29801599..29802945, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25627321..25628667, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene shroud Neighboring gene R and B Neighboring gene Death related ICE-like caspase Neighboring gene uncharacterized protein Neighboring gene non-claret disjunctional Neighboring gene claret Neighboring gene Vacuolar protein sorting 16B

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster. Katewa SD, et al. Cell Metab, 2012 Jul 3. PMID 22768842, Free PMC Article
    2. Nuclear genomic control of naturally occurring variation in mitochondrial function in Drosophila melanogaster. Jumbo-Lucioni P, et al. BMC Genomics, 2012 Nov 22. PMID 23171078, Free PMC Article
    3. The TreadWheel: A Novel Apparatus to Measure Genetic Variation in Response to Gently Induced Exercise for Drosophila. Mendez S, et al. PLoS One, 2016. PMID 27736996, Free PMC Article
    4. The genetic basis of adaptation to copper pollution in Drosophila melanogaster. Everman ER, et al. Front Genet, 2023. PMID 37082199, Free PMC Article
    5. DRONC coordinates cell death and compensatory proliferation. Kondo S, et al. Mol Cell Biol, 2006 Oct. PMID 16980627, Free PMC Article

    See all (47) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables electron transfer activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables electron transfer activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables electron transfer activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    electron transfer flavoprotein beta subunit
    Names
    CG7834-PA
    CG7834-PB
    Etfb-PA
    Etfb-PB
    electron transfer flavoprotein beta-subunit

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      29801599..29802945 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_170428.2 → NP_733307.1  electron transfer flavoprotein beta subunit, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733307.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KHZ6, Q8MR58
      Related
      FBpp0084902
      Conserved Domains (1) summary
      COG2086
      Location:3 → 249
      FixA; Electron transfer flavoprotein, alpha and beta subunits [Energy production and conversion]

    2. NM_143470.2 → NP_651727.1  electron transfer flavoprotein beta subunit, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651727.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KHZ6, Q8MR58
      Related
      FBpp0084901
      Conserved Domains (1) summary
      COG2086
      Location:3 → 249
      FixA; Electron transfer flavoprotein, alpha and beta subunits [Energy production and conversion]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0KHZ6 Q0KHZ6
    Q8MR58 Q8MR58

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous