Rtl3 retrotransposon Gag like 3 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Rtl3provided by MGI
Official Full Name: retrotransposon Gag like 3provided by MGI
Primary source: MGI:MGI:2685221
See related: Ensembl:ENSMUSG00000047686 AllianceGenome:MGI:2685221
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Mar3; ZHC5; Gm375; Mart3; Zcchc5; D430021I08Rik
Summary: Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be located in nucleus. Is expressed in several structures, including 1st branchial arch mandibular component endoderm; alimentary system; immune system; limb; and musculature. Orthologous to human RTL3 (retrotransposon Gag like 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in limb E14.5 (RPKM 47.6) and CNS E14 (RPKM 4.1) See more
Orthologs: human all
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Genomic context

Location:: X D; X 47.37 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (105880688..105884145, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (106837082..106840539, complement)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: retrotransposon Gag-like protein 3

Names: zinc finger CCHC domain-containing protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199468.2 → NP_955762.1 retrotransposon Gag-like protein 3

See identical proteins and their annotated locations for NP_955762.1

Status: VALIDATED

Source sequence(s)

BC064821

Consensus CDS

CCDS30344.1

UniProtKB/Swiss-Prot

Q6P1Y1

Related

ENSMUSP00000060157.10, ENSMUST00000062010.10

Conserved Domains (3) summary

pfam16297
Location:313 → 390

DUF4939; Domain of unknown function (DUF4939)

cl25751
Location:41 → 277

DUF4045; Domain of unknown function (DUF4045)

cl26705
Location:508 → 539

AIR1; Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]